Results 171 to 180 of about 9,424 (215)

PPAR-γ Activation Alleviates Intestinal Dysfunction and Lactose Malabsorption in Experimental Food Allergy Rats. [PDF]

Nutrients
Hao Y, Yao L, Jin Y, Yin S, He Z, Che H.
europepmc   +1 more source

Age-Related Adaptations in Renal Tubular Function in Female Rats. [PDF]

Acta Physiol (Oxf)
Edwards A, Reilly TM, Ralph DL, Tajdini M, Finch AM, Patel A, McFarlin BE, Koepsell H, McDonough AA.   +8 more
europepmc   +1 more source

Effects of starch structure on the absorption of encapsulated amino acids in laying hens fed low-protein diets. [PDF]

Anim Nutr
Yue Z, Wang M, Liu M, Wang X, Zhao J, Jiao H, Lin H.   +6 more
europepmc   +1 more source

Dual SGLT1/2 inhibition with sotagliflozin: a pharmaceutical breakthrough in heart failure management and cardiometabolic risk reduction. [PDF]

Front Med (Lausanne)
Mansour GK, Hammo SB, Sajid MR.
europepmc   +1 more source

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SGLT1 Inhibition: Pros and Cons

European Journal of Pharmacology, 2018
Sodium Glucose Cotransporters 1 (SGLT1) play important roles in the intestinal absorption of glucose and the renal reabsorption of glucose, especially in patients with uncontrolled diabetes and those receiving SGLT2 inhibitors. As a consequence, the inhibition of SGLT1 transporters may represent an interesting therapeutic option in patients with ...
Moses Elisaf, Vasilis Tsimihodimos
exaly   +3 more sources

Development of the Intestinal SGLT1 Transporter in Rats

Molecular Genetics and Metabolism, 2000
Glucose absorption from the small intestine is largely mediated via the sodium-coupled glucose transporter (SGLT1). The goal of this study was to investigate the ontogenesis of the SGLT1, using the rat as an animal model at three stages of development: during lactation, at weaning, and at physiologic maturity.
Saul Teichberg, Mark A Wingertzahn, Raúl A Wapnir   +2 more
exaly   +3 more sources

Stimulation of the glucose carrier SGLT1 by JAK2

Biochemical and Biophysical Research Communications, 2011
JAK2 (Janus kinase-2) overactivity contributes to survival of tumor cells and the (V617F)JAK2 mutant is found in the majority of myeloproliferative diseases. Tumor cell survival depends on availability of glucose. Concentrative cellular glucose uptake is accomplished by Na(+) coupled glucose transport through SGLT1 (SLC5A1), which may operate against a
Zohreh, Hosseinzadeh, Shefalee K, Bhavsar, Manzar, Shojaiefard, Ambrish, Saxena, Katja, Merches, Mentor, Sopjani, Ioana, Alesutan, Florian, Lang   +7 more
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SPAK-Sensitive Regulation of Glucose Transporter SGLT1

The Journal of Membrane Biology, 2014
The WNK-dependent STE20/SPS1-related proline/alanine-rich kinase SPAK is a powerful regulator of ion transport. The study explored whether SPAK similarly regulates nutrient transporters, such as the Na(+)-coupled glucose transporter SGLT1 (SLC5A1). To this end, SGLT1 was expressed in Xenopus oocytes with or without additional expression of wild-type ...
Bernat, Elvira, Maria, Blecua, Dong, Luo, Wenting, Yang, Ekaterina, Shumilina, Carlos, Munoz, Florian, Lang   +6 more
openaire   +3 more sources