Results 21 to 30 of about 27,407 (265)

Sodium-glucose cotransporter-2 inhibitors increase urinary tract infections?—a cross sectional analysis of a nationwide Japanese claims database

open access: yesEndocrine Journal, 2023
Sodium-glucose cotransporter-2 (SGLT2) inhibitors are a novel class of antidiabetic drugs. Guidelines for the proper use of SGLT2 inhibitors recommend caution regarding urinary tract infections (UTIs).
Go Anan   +5 more
doaj   +1 more source

Favorable pleiotropic effects of sodium glucose cotransporter 2 inhibitors: head-to-head comparisons with dipeptidyl peptidase-4 inhibitors in type 2 diabetes patients

open access: yesCardiovascular Diabetology, 2020
Background Sodium glucose cotransporter 2 (SGLT2) inhibitors have shown greater reductions of cardiovascular event risks than dipeptidyl peptidase-4 (DPP4) inhibitors, whereby possible mechanisms may involve the better pleiotropic effects of SGLT2 ...
Shih-Chieh Shao   +7 more
doaj   +1 more source

Benefits of SGLT2 inhibitors in arrhythmias

open access: yesFrontiers in Cardiovascular Medicine, 2022
Some studies have shown that sodium-glucose cotransporter (SGLT) 2 inhibitors can definitively attenuate the occurrence of cardiovascular diseases such as heart failure (HF), dilated cardiomyopathy (DCM), and myocardial infarction. With the development of research, SGLT2 inhibitors can also reduce the risk of arrhythmias.
Jinghan Gao   +6 more
openaire   +3 more sources

A comparison of effects of DPP-4 inhibitor and SGLT2 inhibitor on lipid profile in patients with type 2 diabetes

open access: yesLipids in Health and Disease, 2017
Background Previous studies suggest that dipeptidyl peptidase-4 (DPP-4) inhibitors and sodium glucose cotransporter 2 (SGLT2) inhibitors have different effects on the lipid profile in patients with type 2 diabetes.
Seon-Ah Cha   +7 more
doaj   +1 more source

SGLT2 Inhibitors and the Diabetic Kidney [PDF]

open access: yesDiabetes Care, 2016
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression. Sodium–glucose cotransporter 2 (SGLT2) inhibitors, the most recent glucose-lowering oral agents, may ...
FIORETTO, PAOLA   +4 more
openaire   +3 more sources

Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors [PDF]

open access: yesDiabetes & Metabolism Journal, 2019
BackgroundWe investigated the predictive markers for the therapeutic efficacy and the best combination of sodium-glucose co-transporter 2 (SGLT2) inhibitors (empagliflozin, dapagliflozin, and ipragliflozin) therapy in patients with type 2 diabetes ...
Ji-Yeon Lee   +7 more
doaj   +1 more source

How should we monitor the cardiovascular benefit of sodium–glucose cotransporter 2 inhibition?

open access: yesCardiovascular Diabetology, 2020
Sodium–glucose cotransporter 2 (SGLT2) inhibitors are increasingly prescribed for the treatment of patients with type 2 diabetes to reduce the risk of cardiovascular events, including heart failure (HF).
Atsushi Tanaka, Koichi Node
doaj   +1 more source

Improvement of skeletal muscle insulin sensitivity by 1 week of SGLT2 inhibitor use

open access: yesEndocrine Connections, 2020
Background and Aims: It is currently unclear whether sodium–glucose co-transporter 2 (SGLT2) inhibitor administration can improve the insulin sensitivity as well as rapidly reduce plasma glucose concentrations in humans during the early phase of ...
Yuka Goto   +11 more
doaj   +1 more source

Renoprotective potential of concomittant medications with SGLT2 inhibitors and renin-angiotensin system inhibitors in diabetic nephropathy without albuminuria: a retrospective cohort study

open access: yesScientific Reports, 2023
The renal protective effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors and renin-angiotensin system (RAS) inhibitors on diabetic nephropathy without albuminuria have not been fully investigated.
Tatsuya Ishibashi   +4 more
doaj   +1 more source

Recent UK type 2 diabetes treatment guidance represents a near whole population indication for SGLT2-inhibitor therapy

open access: yesCardiovascular Diabetology, 2023
Recent type 2 diabetes guidance from the UK’s National Institute for Health and Care Excellence (NICE) proposes offering SGLT2-inhibitor therapy to people with established atherosclerotic cardiovascular disease (ASCVD) or heart failure, and considering ...
Katherine G. Young   +6 more
doaj   +1 more source

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