Results 241 to 250 of about 38,769 (305)

Urea cycle modulation by combined SGLT2 inhibitors and metformin. [PDF]

BMC Med
Harada M, Adam J, Han S, Shi M, Ge J, Lintelmann J, Cecil A, Zukunft S, Prehn C, Witting M, Scheerer MF, Neschen S, Irmler M, Beckers J, Adamski J, Teupser D, Linkohr B, Gieger C, de Angelis MH, Peters A, Wang-Sattler R.   +20 more
europepmc   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

The use of SGLT2 inhibitors in older people: What is important? [PDF]

Aging Clin Exp Res
Armentaro G, Maio R, Bencivenga L, Okoye C, Severini G, Cassano V, Zanobbi V, Condoleo V, Bellelli G, Rengo G, Ungar A, Leosco D, Sciacqua A.   +12 more
europepmc   +1 more source

Correspondence: Effects of short‐term tofogliflozin treatment on insulin secretory capacity in type 2 diabetes: Insights and future directions

Journal of Diabetes Investigation, EarlyView.
Gargi Bisht, Nitin Kumar Indora
wiley   +1 more source

Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury

Experimental Physiology, EarlyView.
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley   +1 more source

SGLT2 inhibitors in cardiac amyloidosis: mechanistic insights and clinical perspectives-a narrative review. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Özlek B, Tanik VO.
europepmc   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source

SGLT2 inhibitors in CKD: are they really effective in all patients? [PDF]

Nephrol Dial Transplant
Romagnani P.
europepmc   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Multiple Effects of SGLT2 Inhibitors

JMA Journal
openaire   +2 more sources