Results 121 to 130 of about 35,610 (260)

Suppression of PKM2 by Leonurine Attenuates Alcoholic Hepatitis Through Regulating Glycolytic Reprogramming

Phytotherapy Research, EarlyView.
Leonurine inhibits PKM2 to remodel hepatocyte glycolysis, thereby alleviating liver injury in alcoholic hepatitis. ABSTRACT Alcoholic hepatitis (AH) is a liver disease caused by long‐term heavy drinking. In the early stages, it usually manifests as fatty liver, which can then develop into liver fibrosis and cirrhosis.
Xuan‐Xuan Zhang, Gao‐Feng Pan, Hong Fang, Xiao‐Peng Liu, Jing Sun, Ji‐Xiang Chen, Xin Fan, Jia‐Hao Feng   +7 more
wiley   +1 more source

Defined Extracellular Matrix Contexts Rewire 3D Breast Cancer Cell Models: Effects of Sulfated Hyaluronan in the Expression of Matrix Effector and Matrix-Based Cell Functional Properties. [PDF]

Cancers (Basel)
Vetoulas M, Drosinou M, Alexiou N, Farmaki A, Piperigkou Z, Karamanos NK.   +5 more
europepmc   +1 more source

Essential Oils From the Fruit of Amomum villosum Lour. Alleviate LPS‐Induced Neuroinflammation by Repressing PI3K‐Akt and MAPK Signaling Pathways

Phytotherapy Research, EarlyView.
Amomum villosum essential oil (AVEO) alleviates LPS‐induced neuroinflammation and cognitive and behavioral dysfunction by suppressing PI3K‐Akt and MAPK signaling pathways, modulating inflammatory responses, and restoring metabolic homeostasis, thereby exerting neuroprotective effects. ABSTRACT Amomum villosum Lour.
Hongjin Wang, Xuetong Li, Zhenhai Huang, Shanshan Luo, Jiyu Weng, Shuanghe Wang, Guofeng Shi, Yixi Zeng, Weishan Wen, Lanyue Zhang, Junxia Zheng, Hui Li   +11 more
wiley   +1 more source

Sulfated Hyaluronan Drives Cell Adaptation and Matrix Composition in Advanced 3D Breast Cancer Cell Models. [PDF]

Cells
Koutsakis C, Mineschou K, Spanopoulos K, Mangani S, Franchi M, Karousou E, Piperigkou Z, Karamanos NK.   +7 more
europepmc   +1 more source

Discovery and Fine‐Scale Mapping of Hadal Xenophyophore Habitat in the Nova Canton Trough, Central Pacific Ocean

Remote Sensing in Ecology and Conservation, EarlyView.
Discovery and fine‐scale mapping of a hadal xenophyophore field: submersible video transects and photogrammetry enable semi‐automated delineation of xenophyophores, revealing their abundance, spatial organisation, structural complexity and contribution to habitat heterogeneity at ~8000 m depth.
Denise J. B. Swanborn, Joana Gafeira, Megan Cundy, Daniel C. Bates, Heather A. Stewart, Alan J. Jamieson   +5 more
wiley   +1 more source

Correction: Progress in research on cognitive frailty in the older adults: a narrative review. [PDF]

Front Med (Lausanne)
Shao S, Zhao B, Jin S, Sha L.
europepmc   +1 more source

FinTech and Environmental Sustainability: Evidence From Brazil

Sustainable Development, EarlyView.
ABSTRACT This study explores the dynamic interplay between economic growth and environmental sustainability from a FinTech perspective, using Brazil as a case study. While FinTech's contribution to green transformation, sustainable finance, and resource efficiency has gained increasing attention, a notable lack of empirical research remains to assess ...
Kemal Eyuboglu, Umut Uzar
wiley   +1 more source

Tailored Molecular Scissor Unlocks the Autocatalytic Potential of Hybridization Chain Reaction for Tunable Signal Amplification

Small, EarlyView.
We establish a recycling chain reaction (RCR) using a single hairpin, H3, which disassembles HCR assemblies to unlock the inherent autocatalytic potential of HCR. Conventional HCR is redefined as the fully constrained state (H3 = 0) of RCR. Tuning H3 ratios enables dynamic control over DNA assembly, providing a compact platform for biomolecular ...
Ting Li, Kaiqi Hu, Jiaying Li, Ying Yi Lee, Kin Ming Kwan, Hung‐Wing Li   +5 more
wiley   +1 more source

Adjusting Our Thinking About Feeding Animals: Fiber as the Metric for Mimicking Natural Diets

Zoo Biology, EarlyView.
A typical effect of the change of an animal group to a diet higher in fiber: juveniles keep growing, animals of ideal body weight maintain their weight, and obese individuals lose weight. ABSTRACT Free‐ranging animals often ingest markedly different diets than their counterparts under human care, whether companion animals, production animals, or zoo ...
Marcus Clauss, Geert P. J. Janssens, Oliver Pritchard Moore, Sarah Byrne, Marcin Przybyło   +4 more
wiley   +1 more source

Integrating Qualitative Data Into Learning Health Systems: A Pilot Project With Engaged Student Researchers. [PDF]

Learn Health Syst
Carr T, Spock T, Skrapek C, Heinemann K, King M, Andreas B, Stobart C, Cole C, Plishka C, Ward C, Zheng T, Farthing G, Squair C.   +12 more
europepmc   +1 more source