Results 51 to 60 of about 1,600 (218)
Biological Reviews, EarlyView.ABSTRACT One of the major subfields of chemical ecology is the study of toxins and how they mediate interactions between organisms. Toxins produced by harmful algae (phycotoxins) impact a wide variety of organisms connected to the marine food web. Significant research efforts have thus aimed to identify the ecological and evolutionary drivers behind ...
Milad Pourdanandeh, Erik Selander
wiley +1 more source
On the importance of including both sexes in animal studies – insights from home‐cage monitoring
Biological Reviews, EarlyView.ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater +12 more
wiley +1 more source
CONSTANS-LIKE 7 regulates branching and shade avoidance response in Arabidopsis [PDF]
, 2013 Branching is an important trait of plant development regulated by environmental signals. Phytochromes in Arabidopsis mediate branching in response to the changes in the red light:far-red light ratio (R:FR), the mechanisms of which are still elusive. Here
Lin, Chentao +7 more
core +1 more source
Beyond Closed Loops: Advancing Climate Change Mitigation by Collaborative Open Approaches
Business Strategy and the Environment, EarlyView.ABSTRACT Even as world leaders emphasize the urgency of limiting global warming, a slow transition to a circular economy persists. While climate mitigation efforts focus on renewable energy and efficiency measures, addressing the 45% of emissions from product manufacturing remains critical.
Anna‐Kristin Behnert +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.ISB 2001 is a trispecific antibody that binds to two tumor‐associated antigens (TAA), CD38 and BCMA, and crosslinks to CD3 on T cells resulting in T cell‐mediated cytotoxicity of tumor cells expressing these TAAs. ISB 2001 is currently being tested in relapsed and/or refractory multiple myeloma (RRMM) patients in the first‐in‐human (FIH) TRIgnite‐1 ...
Vinu Chandralayam Ayyappa Menon +11 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
A constitutive shade-avoidance mutant implicates TIR-NBS-LRR proteins in Arabidopsis photomorphogenic development [PDF]
, 2006 11 pages, 10 figures.-- PMID: 17114357 [PubMed].-- PMCID: PMC1693933.-- Supplementary information available at: http://www.plantcell.org/cgi/content/full/tpc.105.038810/DC1In plants, light signals caused by the presence of neighbors accelerate stem ...
Yanovsky, Marcelo J. +13 more
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 980-997, April 2025.Abstract Heart failure (HF) creates a considerable clinical, humanistic and economic burden on patients and caregivers as well as on healthcare systems. To attenuate the significant burden of HF, there is a need for enhanced management of patients with HF.
Javed Butler +8 more
wiley +1 more source
A guide to neuromodulation in drug‐resistant epilepsy
Epileptic Disorders, EarlyView.Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh +10 more
wiley +1 more source
The role of phytohormones in the shade avoidance syndrome
, 2005 Bibliography: p.
openaire +2 more sources