Results 201 to 210 of about 660,737 (282)
Transparent Topological Meta‐Diplexer via Tightly Confined Valley Surface States
Advanced Science, EarlyView.An optically transparent topological metasurface supporting tightly confined valley surface states enables robust and flexible wave routing in an ultrathin platform. A compact transparent meta‐diplexer with spatially and spectrally separated channels is realized, while communication experiments verify high‐fidelity signal transmission, opening new ...
Sijie Li +5 more
wiley +1 more source
Enviromics and Abiotic Enviromics: Enhancing Stress Biology and Plant Resilience Breeding
Advanced Science, EarlyView.Environmental stressors are captured through high‐throughput envirotyping and integrated into an enviromic framework with genomic, transcriptomic, phenomic, and environmental data. AI/ML models enable prediction and guide marker‐assisted selection, genomic selection, genome editing, and gene pyramiding toward improved abiotic stress tolerance, yield ...
Guangchao Sun +6 more
wiley +1 more source
A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy
Advanced Science, EarlyView.A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao +14 more
wiley +1 more source
Advanced Science, EarlyView.Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan +16 more
wiley +1 more source
Advanced Science, EarlyView.A polymer chain in motion: backbone, ring, and counterion dynamics interlock across timescales to relay protons through poly(ionic liquid) membranes. ABSTRACT Polymer electrolyte membranes composed of ionic liquids (IL), capable of conducting protons efficiently at elevated temperatures, without external humidification, could transform fuel cell ...
Keenan Smith +11 more
wiley +1 more source
Advanced Science, EarlyView.Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne +15 more
wiley +1 more source
Advanced Science, EarlyView.This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou +4 more
wiley +1 more source
Advanced Science, EarlyView.A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu +11 more
wiley +1 more source
Advanced Science, EarlyView.Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi +8 more
wiley +1 more source
Conformal Reconfigurable Intelligent Surfaces: A Cylindrical Geometry Perspective
Advanced Electronic Materials, EarlyView.Cylindrical reconfigurable intelligent surfaces are explored for low‐complexity beam steering using one‐bit meta‐atoms. A multi‐level modeling approach, including optimization‐based synthesis, demonstrates that even minimal hardware can support directive scattering.
Filippo Pepe +4 more
wiley +1 more source