Results 211 to 220 of about 551,411 (283)

A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy

Advanced Science, EarlyView.
A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao, Yufei Lan, Min‐Goo Lee, Jinjun He, Yueran Pan, Eunji Kim, Xin Fu, Sungwook Jung, Wanxia Lu, Jinyue Fan, Haoxiang Chen, Yuanbo Zhao, Yuling Xu, Jong Seung Kim, Chao Zhang   +14 more
wiley   +1 more source

Convergent Evolution towards High Net Carbon Gain Efficiency Contributes to the Shade Tolerance of Palms (Arecaceae). [PDF]

PLoS One, 2015
Ma RY, Zhang JL, Cavaleri MA, Sterck F, Strijk JS, Cao KF.   +5 more
europepmc   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Correlated Polymer‐Proton Hopping Enables Water‐Independent Fast Proton Transport in Poly(Ionic Liquid) Membranes

Advanced Science, EarlyView.
A polymer chain in motion: backbone, ring, and counterion dynamics interlock across timescales to relay protons through poly(ionic liquid) membranes. ABSTRACT Polymer electrolyte membranes composed of ionic liquids (IL), capable of conducting protons efficiently at elevated temperatures, without external humidification, could transform fuel cell ...
Keenan Smith, Antonela Gallastegui, Zixuan Yu, Yuliana Pairetti, Andrew Seel, Jacques Ollivier, Victoria Garcia Sakai, Bob C. Schroeder, Maria Forsyth, Aurelie Gueguen, David Mecerreyes, Fabrizia Foglia   +11 more
wiley   +1 more source

Specific leaf area modulates but does not explain the association between abiotic stress tolerance and insect feeding guild prevalence in Northern Hemisphere woody plants. [PDF]

Ann Bot
Cerdeira-Pérez A, Laanisto L, Pavanetto N, Puglielli G.   +3 more
europepmc   +1 more source

Conformal Reconfigurable Intelligent Surfaces: A Cylindrical Geometry Perspective

Advanced Electronic Materials, EarlyView.
Cylindrical reconfigurable intelligent surfaces are explored for low‐complexity beam steering using one‐bit meta‐atoms. A multi‐level modeling approach, including optimization‐based synthesis, demonstrates that even minimal hardware can support directive scattering.
Filippo Pepe, Ivan Iudice, Giuseppe Castaldi, Marco Di Renzo, Vincenzo Galdi   +4 more
wiley   +1 more source

Densely packed needles along the shoots of evergreen conifers exhibit shade-acclimated photosynthetic characteristics even under full sunlight. [PDF]

Ann Bot
Kitao M, Yazaki K, Sugai T, Harayama H, Agathokleous E, Tanaka R.   +5 more
europepmc   +1 more source

Fundamental Challenges, Physical Implementations, and Integration Strategies for Ising Machines in Large‐Scale Optimization Tasks

Advanced Electronic Materials, EarlyView.
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley   +1 more source

Anion‐Cation Synergistic Passivation for High‐Performance FA‐Cs Halide Perovskite Photodetectors

Advanced Electronic Materials, EarlyView.
An anion‐cation synergistic passivation strategy is developed to improve perovskite photodetectors. Surface‐localized DMePDA2+ cations and bulk‐diffused Cl− anions simultaneously reduce defects, enhancing charge transport and suppressing recombination.
Hyeon‐Jong Shin, Kwang‐Ro Yun, Tae Joon Park, Tae‐Yeon Seong   +3 more
wiley   +1 more source

Research on the Physiological Response Mechanism and Expression of Key Leaf Color Genes in 'Duojiao' Crabapple Under Partial Shading. [PDF]

Plants (Basel)
Chen B, Wang M, Yang Y, Li L, Fan Y, Zong X, Guo X, Zou F, Lin Q, Yu H, Yu J, Zhang M, Mao Y, Shen X.   +13 more
europepmc   +1 more source