Results 151 to 160 of about 240,622 (303)

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen, Vinh Hoa Pham, Richard M. Hoglund, Joel Tarning, Junjie Ding   +4 more
wiley   +1 more source

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

Spatial metrics in fire ecology: seeking consistency amidst complexity

Biological Reviews, EarlyView.
ABSTRACT Technological advances, including remote sensing, have led to a proliferation of metrics used in ecological studies to examine spatial patterns of fire regimes and their ecological effects. Researchers can use many different metrics to analyse spatial variation in both fire events and resulting fire regimes, including fire size, shape ...
Alexander R. Carey, Geoffrey J. Cary, Teigan Cremona, Hugh F. Davies, Brett P. Murphy, Sam C. Banks   +5 more
wiley   +1 more source

The Benefits of Community-Level Efforts to Increase Tree Shade Availability for Cancer Prevention and Control. [PDF]

Public Health Rep
Holman DM, Mallen ES, Reza A, Townsend JS, Kava CM.   +4 more
europepmc   +1 more source

A roadmap to key traits of invasive Drosophilidae

Biological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck, Bréa Raynaud‐Berton, Méghan Boulembert, Olivier Chabrerie, Aude Couty, Franck Dedeine, Patrice Eslin, Vincent Foray, Romain Georges, Patricia Gibert, Laurence Mouton, Sylvain Pincebourde, David Renault, Christelle Suppo, Hervé Colinet   +14 more
wiley   +1 more source

Effects of natural and artificial shade on behavior, physiology, and productivity in water buffalo: a narrative review. [PDF]

Front Vet Sci
Mota-Rojas D, Lanzoni L, Fernandes Bettencourt A, Domínguez-Oliva A, Chay-Canul A, Álvarez-Macías A, Bragaglio A, Hernández-Avalos I, Fischer V, Nannoni E, Abd El-Aziz AH, Mora-Medina P, Martínez-Burnes J, Olmos-Hernández A, Torres-Bernal F, José-Pérez N, Barile VL.   +16 more
europepmc   +1 more source

Ecology and evolution of pyrazines in insects

Biological Reviews, EarlyView.
ABSTRACT Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen‐containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and ...
Zowi Oudendijk, Niklas Wahlberg, Johanna Mappes   +2 more
wiley   +1 more source

Global patterns of inequality in pedestrian shade provision. [PDF]

Nat Commun
Gu X, Beuster L, Liu X, van Leeuwen E, Venverloo T, Duarte F.   +5 more
europepmc   +1 more source

A mosaic of microclimates: biodiversity outcomes and wildlife habitat potential in large‐scale solar facilities

Biological Reviews, EarlyView.
ABSTRACT The rapid global expansion of photovoltaic (PV) solar facilities, now comprising nearly 80% of the recent and projected growth of renewable electricity, represents one of the most significant land‐use changes of the 21st century. While PV facilities are critical for decarbonising energy systems, their large spatial footprint and infrastructure
Tom Armstrong, Caleb L. Loughran, Joshua R. Ennen, Kristoffer H. Wild, Eric J. Nordberg   +4 more
wiley   +1 more source

Spring ephemeral Erythronium umbilicatum may not be vulnerable to phenological mismatch with overstory trees. [PDF]

Am J Bot
Schopler M, Simha A, Dalton RM, Wilson EM, Redick E, Youngsteadt E, Petry WK.   +6 more
europepmc   +1 more source