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Untangling Tau: Molecular Insights into Neuroinflammation, Pathophysiology, and Emerging Immunotherapies

open access: yesCurrent Issues in Molecular Biology, 2023
Neuroinflammation, a core pathological feature observed in several neurodegenerative diseases, including Alzheimer’s disease (AD), is rapidly gaining attention as a target in understanding the molecular underpinnings of these disorders.
Ryder Davidson   +5 more
doaj   +1 more source

Ketamine and the Disinhibition Hypothesis: Neurotrophic Factor-Mediated Treatment of Depression

open access: yesPharmaceuticals, 2023
Ketamine is a promising alternative to traditional pharmacotherapies for major depressive disorder, treatment-resistant depression, and other psychiatric conditions that heavily contribute to the global disease burden. In contrast to the current standard
Philip Borsellino   +4 more
doaj   +1 more source

Expression of miR-720 is correlated with DNMT3 in Oral squamous cell carcinomas [PDF]

open access: yesExRNA, 2020
Background: Many factors are involved with cellular differentiation and pluripotency, such as long non-coding and microRNAs (miRNA). miR-720 has been demonstrated to affect development, differentiation and pluripotency in dental pulp stem cells but has ...
Andrew Graves   +2 more
doaj   +1 more source

Extranodal manifestation of mantle cell lymphoma in the submandibular duct: A case report and review of literature

open access: yesOtolaryngology Case Reports, 2023
The vast majority of oral cavity malignancies are primary squamous cell carcinomas. Far less common are lymphomas, sarcomas, and secondary cancers. We present an interesting case of a patient with relapsed lymphoma that presented as a submandibular duct ...
Spencer Muscelli   +2 more
doaj   +1 more source

Assessment of MicroRNA (miR)-365 Effects on Oral Squamous Carcinoma Cell Line Phenotypes

open access: yesBiomolecules, 2021
miR-365 is a microRNA that regulates transcription and has been demonstrated to promote oncogenesis and metastasis in some cancers while suppressing these effects in others.
Jeffrey Coon, Karl Kingsley
doaj   +1 more source

Detection of Direct Sun Glare on Drivers from Point Clouds

open access: yesRemote Sensing, 2022
Sunlight conditions can reduce drivers’ visibility, which is a safety concern on road networks. This research introduces a method to study sun glare incidence in road environments.
Silvia María González-Collazo   +3 more
doaj   +1 more source

The shame of the Woman on the Rock [PDF]

open access: yesBaština, 2022
Through its focus on the stream of thoughts of Marta L, overwhelmed by worry over the obvious signs of aging, Andrić's story The Woman on the Rock naturally encourages psychological interpretations.
Ahmetagić Jasmina M.
doaj   +1 more source

Evaluation of Hyaluronic Acid to Modulate Oral Squamous Cell Carcinoma Growth In Vitro

open access: yesJournal of Functional Biomaterials, 2020
Introduction: Previous studies have demonstrated that glycosaminoglycan hyaluronic acid (HA) is capable of mediating oral tumor growth. Some clinical evidence has suggested reduced HA expression predicts poor cancer prognosis and that HA-chemotherapy ...
Jordan Ringer   +2 more
doaj   +1 more source

Destination choice modeling with spatially distributed constraints

open access: yesJournal of Transport and Land Use, 2023
Destination choice models are a key component of any transport and land-use model. Applications in agent-based models allow for destination choice on an individual level including personal variables, like trip purpose, or situational variables.
Basil Vitins, Alexander Erath
doaj   +1 more source

The Role of Gut Microbiota in Orthopedic Surgery: A Systematic Review

open access: yesMicroorganisms
The human gut microbiome represents a complex ecosystem comprising numerous microorganisms critical to basic physiological processes. The gut microbiome’s composition and functionality influence surgical outcomes following orthopedic procedures.
Ahmed Nadeem-Tariq   +5 more
doaj   +1 more source

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