Results 101 to 110 of about 1,598,510 (299)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingThe undulating terrain in mountainous and hilly regions results in a greater variety and complexity of shadows. Efficient methods for shadow detection and reconstruction in high-resolution remote sensing images are particularly important in such hilly ...
Zhenqing Wang +5 more
doaj +1 more source
Hybrid feature‐based moving cast shadow detection
IET Computer VisionAbstract The accurate detection of moving objects is essential in various applications of artificial intelligence, particularly in the field of intelligent surveillance systems. However, the moving cast shadow detection significantly decreases the precision of moving object detection because they share similar motion characteristics ...
Jiangyan Dai +4 more
openaire +2 more sources
Small Businesses and the Shadow Economy [PDF]
This paper investigates causalities between small businesses and the shadow economy in ten New Member States of the European Union in the years 2000–2005. The transition from a centrally planned to a market economy, with deregulation and privatization of
Bojan Nastav, Štefan Bojnec
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Geo-spatial Information ScienceThis research work proposes a novel cost calculation method that considers shadow occlusion areas to address the issues of poor disparity estimation in urban areas, termed Matching Cost based on Shadow Properties (MCSP), error estimation of the shadow ...
Hongjun Sha +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Cost-Constrained Multi-label Group Feature Selection Using Shadow Features
We consider the problem of feature selection in multi-label classification, considering the costs assigned to groups of features. In this task, the goal is to select a subset of features that will be useful for predicting the label vector, but at the same time, the cost associated with the selected features will not exceed the assumed budget.
Tomasz Klonecki +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source