Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Selective Aqueous Chemical Solution Deposition Using Patterned Self-Assembling Monolayers. [PDF]
Neeleman K +4 more
europepmc +1 more source
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita +4 more
wiley +1 more source
Imaging Results from a Direct Conversion X-ray Detector with TlBr and CMOS Pixel Array. [PDF]
Christian JF +12 more
europepmc +1 more source
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
Flexible and Stretchable Microneedle Electrode Arrays by Soft Lithography for Continuous Monitoring of Glucose. [PDF]
Choi YH +5 more
europepmc +1 more source
We introduce a vision‐based real‐time monitoring system for additive manufacturing that detects subtle moisture‐induced degradation via a diffusion model‐based framework. The approach enables nondestructive assessment of moisture‐induced damage level and mechanical performance and establishes a practical route toward more intelligent, reliable, and ...
Jiyoung Jung +4 more
wiley +1 more source
Cooperative Solvent-Thermal Interactions Enable Multi-Material Nanotransfer Printing for Multi-Dimensional Molecular Profiling. [PDF]
Park TW +12 more
europepmc +1 more source
Real‐Time Ferroelectric Domain Wall Dynamics During Electric Poling and Depoling
Real‐time visualization of domain wall dynamics during alternating‐current poling, direct‐current poling, and electrical depoling in relaxor‐PT ferroelectric single crystals reveals distinct field‐dependent pathways and strong path dependence. Instant polarized light microscopy uncovers reversible domain wall nucleation, motion, and reconfiguration ...
Ziqi Wang +12 more
wiley +1 more source
Low-temperature, vacuum-free deposition of N-DMBI-H enables high conductivities in organic semiconductors. [PDF]
Ferrari F, Pokerznik O, Koster LJA.
europepmc +1 more source

