Results 61 to 70 of about 163,799 (293)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PROBLEM ASPECTS OF IDENTIFICATION THE FACTORS OF SHADOWING OF ENVIRONMENTAL TAXATION IN UKRAINE

open access: yesСоціальна економіка, 2022
In order to overcome the reasons for the environmental tax not fulfilling its compensatory, stimulating and fiscal functions, the need to study the problems of environmental taxation through the prism of the growth of the shadow economy and corruption in
Iana Kobushko   +2 more
doaj   +1 more source

Non-equilibrium initial conditions from pQCD for RHIC and LHC [PDF]

open access: yes, 1999
We calculate the initial non-equilibrium conditions from perturbative QCD (pQCD) within Glauber multiple scattering theory for $\sqrt s =200$ AGeV and $\sqrt s =5.5$ ATeV.
A.H. Mueller   +23 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Testing a 5G Communication System: Kriging-Aided O2I Path Loss Modeling Based on 3.5 GHz Measurement Analysis

open access: yesSensors, 2021
Deep knowledge of how radio waves behave in a practical wireless channel is required for the effective planning and deployment of radio access networks in outdoor-to-indoor (O2I) environments.
Melissa Eugenia Diago-Mosquera   +2 more
doaj   +1 more source

Nuclear shadowing at low Q^2 [PDF]

open access: yes, 2003
We re-examine the role of vector meson dominance in nuclear shadowing at low Q^2. We find that models which incorporate both vector meson and partonic mechanisms are consistent with both the magnitude and the Q^2 slope of the shadowing data.Comment: 7 ...
A. Capella   +41 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Coverage Improvements for Sub-Terahertz Systems Under Shadowing Conditions

open access: yesJournal of Telecommunications and Information Technology, 2023
Radio propagation in the millimeter wave and sub-terahertz domain is heavily affected by shadowing conditions. The communication link is blocked without any additional technical means being used. Coverage improvements can be provided by using reflectors,
Werner Mohr
doaj   +1 more source

Shadow links

open access: yesJournal of Economic Theory, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Förster, Manuel   +2 more
openaire   +5 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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