Results 41 to 50 of about 1,542,085 (298)
Architectural Engineering Earthquake Shake Table [PDF]
, 2013 The Architectural Engineering Department at California Polytechnic State University, San Luis Obispo, owns and operates a single-axis earthquake shake table that previously was only capable of basic wave motion.
Williams, Brandan +2 more
core
Motion analysis of furniture under seismic excitation using the finite element method
Japan Architectural Review, 2018 Improperly secured furniture, especially on the upper floors of high‐rise buildings under long‐period ground motion, can prove dangerous to human life. Fallen items of furniture such as chairs and desks could become fatal obstacles that prevent efficient
Daigoro Isobe +5 more
doaj +1 more source
, 2020 This file is a Persian written article demonstrating a geotechnical shaking table test in 1g.
openaire +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
An Analytical Solution for Block Toppling Failure of Rock Slopes during an Earthquake
Applied Sciences, 2017 Toppling failure is one of the most common failure types in the field. It always occurs in rock masses containing a group of dominant discontinuities dipping into the slope.
Songfeng Guo +4 more
doaj +1 more source
Dizhen xuebao, 2023 对振动台在大行程移动过程中导轨不平顺引起的倾斜效应进行了理论分析，选择0.1 Hz及以下频点开展振动台导轨不平顺引起的台面倾斜对测试结果影响的定量化分析。结果表明，振动台面在移动过程中的不确定倾斜对地震计水平分量灵敏度的影响大于对垂直分量灵敏度的影响。采用高精度水平仪获取水平振动台在不同行程下的运动轨迹起伏变化，并基于倾斜效应的影响机制，用Labview语言实现补偿系统，在地震计的振动测试中对测试结果进行动态补偿。测试结果表明，经过动态补偿，导轨不平顺不再对灵敏度校准结果存在明显制约 ...
Jiemei Ma, Xiaoyong Fan, Wen He
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source