Results 251 to 260 of about 4,288,299 (311)

Synthesis of tunable copolymers of 3-hydroxybutyrate and 3-hydroxyvalerate by engineered <i>Halomonas bluephagenesis</i> and their characterizations. [PDF]

open access: yesSynth Syst Biotechnol
Li S   +11 more
europepmc   +1 more source

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

open access: yesAdvanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo   +16 more
wiley   +1 more source

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai   +11 more
wiley   +1 more source

Cadmium-tolerant root microbes reduce cadmium accumulation in <i>Ligusticum chuanxiong</i> Hort. [PDF]

open access: yesPeerJ
Yu Z   +10 more
europepmc   +1 more source

A facile approach based on test strip for on-site determination of glucose in tobacco matrices. [PDF]

open access: yesFront Chem
Cai K   +9 more
europepmc   +1 more source

Combining computer-aided enzyme design and chromosomal integration for plasmid-free biosynthesis of 1,5-pentanediol in Escherichia coli. [PDF]

open access: yesMicrob Cell Fact
Deng H   +10 more
europepmc   +1 more source

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