Results 61 to 70 of about 1,330,874 (154)
Abstract Introduction The transition from student to doctor represents a challenging shift in identity and responsibility that many graduates find difficult to manage. To understand better how to support the transition to practice we need an exploration of graduates' experiences that does not see the transition as a single moment, but a continuous ...
Stuart Redvers Pattinson +2 more
wiley +1 more source
Forensic and clinical diagnosis in "shaken baby syndrome", between child abuse and iatrogenic abuse
“Shaken baby syndrome” in child abuse cases is a challenge for pediatrician and forensic experts, often a diagnosis of exclusion, with overwhelming moral and legal implications.
Roxana M. Duncea +3 more
doaj +1 more source
Metformin suppresses ATF2 expression, activating the PI3K/Akt pathway and promoting Nrf2 nuclear translocation. This upregulates GPX4, inhibiting ferroptosis in trophoblast cells. Erastin blocks system Xc−, depleting GSH and promoting ferroptosis. LY294002 and ML385 inhibit the pathway, validating the mechanism.
Dandan Xia +6 more
wiley +1 more source
Knowing, recognizing, and preventing shaken baby syndrome: The role of primary care pediatrician
The Shaken Baby Syndrome (SBS) is the result of a severe form of physical abuse inflicted on children under the age of 2, mostly by parents or other caregivers, to quiet their inconsolable crying.
Anna Libera Latino +3 more
doaj +1 more source
Abstract Objective Ketogenic dietary therapies can reduce seizure frequency in drug‐resistant epilepsy, but adherence to the classical ketogenic diet is often poor. Intermittent fasting supplemented with medium‐chain triglycerides (MCTs) may offer a more feasible and less restrictive alternative.
Wiebke Hahn +11 more
wiley +1 more source
Tato bakalářská práce pojednává o syndromu třeseného dítěte. Hlavním cílem práce je vyhledat, sumarizovat a analyzovat dostupné informace o syndromu třeseného dítěte.
Rybová, Karolína
core +2 more sources
This study demonstrated that administration of Lacticaseibacillus rhamnosus LRPerfectus158 significantly alleviated IBS‐like symptoms in a mouse model by attenuating visceral hypersensitivity, reducing intestinal inflammation, improving epithelial barrier function, and relieving anxiety‐like behaviors.
Dun Su +11 more
wiley +1 more source
Oestrogen modulates stress‐induced vagally‐dependent gastric responses to oxytocin
Abstract figure legend In female rats, PVNCRF‐DMV neurons and DMV CRF1 receptors are tonically active, allowing oxytocin (OXT) to modulate inhibitory GABAergic transmission to DMV neurons. Parasympathetic control of gastric functions involves engagement of non‐adrenergic non‐cholinergic vagal efferent pathways, but recruitment of distinct pathways ...
Ruchi Bhagat +2 more
wiley +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Background: The purpose of this study is to make an overview of the assumed pathogenic mechanisms underlying Shaken baby syndrome and the differential diagnoses that have to be considered when diagnosing an infant with presumed Shaken baby syndrome (SBS).
Poulsen, Silje Østerholt
core

