Results 31 to 40 of about 913,160 (305)

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

The Rockefeller Foundation’s Unrealized “Shanghai Medical School” Plan and Its Implications (1915–1920) [PDF]

Uisahak
This study aims to explore the Rockefeller Foundation (RF)’s vision for medical education in China through an analysis of the “Shanghai Medical School” proposal and to evaluate the implications of its abandonment on both medical education in Shanghai and
Jeongeun JO
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Simulation of extreme compound coastal flooding in Shanghai

Shui kexue jinzhan, 2019
Estuary deltas and coastal cities are facing with the rising risk of the compound flooding due to the coincidence of storm surge,extreme precipitation,high tide and high river discharge. A new integrated numerical modeling system,which coupled atmosphere,
WANG Luyang, ZHANG Min, WEN Jiahong, CHONG Zhentao, YE Qinghua, KE Qian   +5 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

In-migration to suburban towns of Shanghai, 1980 - 87 [PDF]

, 1989
The thesis studies the town-oriented migration and the socio-economic development of towns in the suburbs of Shanghai during 1980 - 87. Since the Chinese government started the economic reforms in 1978, an impressive nationwide rural-urban migration has ...
Jiang, Liang
core  

Trends in prevalence of coexistence of hypertension and diabetes mellitus among residents aged 35 – 74 years in Shanghai, 2002 – 2017: a surveillance data analysis

Zhongguo gonggong weisheng
ObjectiveTo estimate the trend in the coexistence of hypertension and diabetes mellitus (HTN-DM) among residents aged 35 – 74 years in Shanghai during 2002 – 2017 for the prevention and control of the comorbidity.MethodsThe study data were from four ...
Ke CAO, Yang ZHENG, Qinping YANG, Yanyun LI, Qundi YANG, Xiaoxia LIU, Han WU, Chaowei FU, Danni LIU, Yan SHI   +9 more
doaj   +1 more source

Comparative Advantages of Free Trade Port Construction in Shanghai under the Belt and Road Initiative

International Journal of Financial Studies, 2020
As China’s opening-up grows wider under the Belt and Road Initiative, the exploration and construction of free trade ports have received increasing attention.
Hao Hu, Shufang Wang, Jin-liao He
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source