Results 91 to 100 of about 881,333 (286)
IEEE AccessLarge Language Models (LLMs) empowered agents are effective across various tasks and demonstrate outstanding performance, which can be further enhanced through collaboration with multiple LLM agents. The current approaches for collaboration with multiple
Anan Jin +3 more
doaj +1 more source
Advanced Science, EarlyView.A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi +6 more
wiley +1 more source
Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D
Advanced Science, EarlyView.CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
A critical examination of film tourism planning and management in Portugal
Dos AlgarvesFilm tourism has gained significant notoriety in recent years, emerging as a prominent phenomenon to promote destinations, attract visitors, and stimulate economic and social development.
Isa Neves, Kelly Maguire, Nuno Almeida
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Surface Graphitized Mesoporous Carbon Surpasses the Conductivity–Porosity Trade‐Off
Advanced Science, EarlyView.Electrochemical cathodic polarization in molten CaCl2‐NaCl converts mesoporous carbon (MC) into surface‐graphitized mesoporous graphite, simultaneously increasing surface area (397–867 m2/g) and electrical conductivity (26–450 S/cm) without mass loss.
Juntian Fan +12 more
wiley +1 more source
GelsFungal infections pose a significant yet under-recognised global health burden, affecting over one billion individuals annually and contributing to approximately 2.5 million direct deaths.
Daniel P. Fitzpatrick +4 more
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Advanced Science, EarlyView.A self‐regulated Escherichia coli Nissle 1917 strain equipped with a dual‐key genetic circuit achieved antibiotic‐free stability and programmable lysis for therapeutic protein delivery. By co‐expressing an IL‐2 mutant and Amuc_1100, the engineered bacteria restored immune balance and epithelial integrity, providing a safe and precise approach for ...
Shuaijie Ding +6 more
wiley +1 more source
, 2022 AbstractAccording to Shannon, a message x is a random event. Let p(x) be the probability of occurrence of event x. If $$p(x)=0$$ p ( x ) = 0 , this event does not occur; If $$p(x)=1$$
openaire +1 more source
Advanced Science, EarlyView.Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai +12 more
wiley +1 more source