Results 201 to 210 of about 29,533 (242)

Integrating Immunotherapy Into Head and Neck Surgery: Bridging Tumor Biology to Perioperative Decision‐Making, a Review

Head &Neck, EarlyView.
ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
wiley   +1 more source

Superior Labial Artery Mucosal Flap (SLAM) for Reconstruction of Major Lower Lip Mucosal Defects

Head &Neck, EarlyView.
ABSTRACT Background The superior labial artery mucosal (SLAM) flap is a versatile, pedicled axial flap ideally suited for mucosal lining in lower lip reconstruction. Methods This article details the surgical anatomy and technique of the SLAM flap, highlighting its role as a standalone liner or mucosal adjunct to microvascular free tissue transfer in ...
Nicholas Shannon, Takako Eva Yabe, Bruce Ashford   +2 more
wiley   +1 more source

Impact of Quantum Non-Locality and Electronic Non-Ideality on the Shannon Entropy for Atomic States in Dense Plasma. [PDF]

Entropy (Basel)
Nuraly AT, Seisembayeva MM, Dzhumagulova KN, Shalenov EO.   +3 more
europepmc   +1 more source

Host‐specific and deterministic microbiome assembly in major coleopteran stored‐grain pests

iMetaOmics, EarlyView.
Dual DNA‐ and RNA‐based sequencing profiled the microbiomes of five major coleopteran stored‐grain pests and their wheat flour substrate. The microbiomes differed significantly among hosts and from flour, yet 11 core bacterial and 9 core fungal taxa were shared across hosts. RNA data revealed host‐specific active microbiota.
Abrar Muhammad, Xiaoqiang Shen, Lichao Chen, Enhui Guo, Huarui Zhang, Xiaoyu Lei, Chao Sun, Jianhua Lv, Yongqi Shao   +8 more
wiley   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

Last‐minute coordination: Adapting to demand to support last‐mile operations

Journal of Operations Management, Volume 71, Issue 2, Page 176-194, March 2025.
Abstract In the highly competitive e‐commerce industry, customer‐facing warehouses are crucial as the “order penetration points” for e‐commerce last‐mile operations. This research examines how warehouses use last‐minute coordination, an unstructured mechanism, to ensure sufficient inventory at the order penetration points. Previous research has focused
Kedong Chen, Hung‐Chung Su, Kevin Linderman, William Li   +3 more
wiley   +1 more source

Association between blenderized tube feeds and differential oropharynx, stomach, and stool microbiome signatures relative to conventional formula feeds in children fed via enteral tube: A cross‐sectional study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Blenderized gastrostomy tube feeds are associated with reduced gastrointestinal symptoms. We hypothesize that patients receiving blenderized tube feeds, compared with standard formula, will have less gastric‐oropharyngeal microbial overlap, a possible biomarker of less gastroesophageal refluxate, and differences in beta diversity in
Bridget M. Hron, Yanjia Jason Zhang, Clare Golden, Christopher Chalmers, Grace Nemec, Elise Delaney, Evrim Ozcan, Michael Kim, Lauren Jalali, Toni Solari, Jasper Brezsny‐Feldman, Eric J. Alm, Lynn Bry, Rachel Rosen   +13 more
wiley   +1 more source

Periodontitis during pregnancy: The effect on the gut microbiome and intestinal inflammation

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis has been epidemiologically associated with adverse pregnancy outcomes, but causality remains difficult to establish in humans due to confounding factors. This study uses a controlled murine model to examine the effects of experimentally induced periodontitis on the composition of the gut microbiota and gastrointestinal
Richard Bright, Matthew G. Macowan, Keyuan Tian, Tracy Fitzsimmons, Rebecca L. Wilson, Claire T. Roberts, Claus T. Christophersen, Peter M. Bartold, Stephen P. Kidd, Peter S. Zilm   +9 more
wiley   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source