Results 221 to 230 of about 88,634 (286)

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

open access: yesInterdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li   +24 more
wiley   +1 more source

Decadal Changes of UV Aerosol Optical Depth in Hobart, Australia Measured With a Brewer MKIII: Relationship to Bushfire Events and Climate Indices

open access: yesInternational Journal of Climatology, EarlyView.
Monthly average aerosol optical depth at 320 nm obtained with a Brewer MKIII spectrophotometer for Hobart, Australia (42.8806° S, 147.3250° E) over a 21‐year period. There is a linear trend of 15.4% per decade. There are 9 months when the average aerosol optical depth exceeds twice the monthly standard deviation.
Manuel Nuñez   +3 more
wiley   +1 more source

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim   +5 more
wiley   +1 more source

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