Results 31 to 40 of about 7,802,073 (345)

An engineered U7 small nuclear RNA scaffold greatly increases ADAR-mediated programmable RNA base editing

Nature Communications
Custom RNA base editing exploiting the human Adenosine Deaminase Acting on RNA (ADAR) enzyme may enable therapeutic gene editing without DNA damage or use of foreign proteins.
Susan M. Byrne, Stephen M. Burleigh, Robert Fragoza, Yue Jiang, Yiannis Savva, Ricky Pabon, Evan Kania, Joseph Rainaldi, Andrew Portell, Prashant Mali, Adrian W. Briggs   +10 more
doaj   +1 more source

Shaping speech [PDF]

Down Syndrome Research and Practice, 2007
Clear speech can often be challenging for people with Down syndrome. The shape of the hard palate in the top of the mouth influences speech production. A new paper reports detailed measures of the shape and size of the hard palate among children with Down syndrome.
openaire   +2 more sources

Shape Theory

Journal of Mathematical Sciences, 2021
Shape theory was founded by K.~Borsuk 50 years ago. In essence, this is spectral homotopy theory; it occupies an important place in geometric topology. The article presents the basic concepts and the most important, in our opinion, results of shape theory.
openaire   +2 more sources

Perceptually Motivated Shape Context Which Uses Shape Interiors

, 2012
In this paper, we identify some of the limitations of current-day shape matching techniques. We provide examples of how contour-based shape matching techniques cannot provide a good match for certain visually similar shapes.
Kakarala, Ramakrishna, Premachandran, Vittal   +1 more
core   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

THE INFLUENCE OF POLITICAL LIBERALISM ON THE WESTERN WAY OF WARFARE [PDF]

Annals: Series on Military Sciences, 2020
Throughout human history, War used to be one of the most serious state affairs, maybe the most important one. Wars that were well conceived and well led had all chances to improve the status of entities, states and protostates, acting in a “world ...
Paul Alexandru Sanda
doaj  

Event shape sorting

, 2016
We propose a novel method for sorting events of multiparticle production according to the azimuthal anisotropy of their momentum distribution. Although the method is quite general, we advocate its use in analysis of ultra-relativistic heavy-ion ...
Kopecna, Renata, Tomasik, Boris
core   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

TECHNOLOGICAL DEVELOPMENT AND THE CONTEMPORARY MILITARY PHENOMENON. IMPLICATIONS OF THE NEW TECHNOLOGIES [PDF]

Annals: Series on Military Sciences, 2020
In its multi-millennial evolution, humanity has been strongly marked by smaller or larger conflicts that have decisively placed their imprint on technological progress and on the application of military power implicitly. The extremely rapid succession
Aurel Bucur
doaj  

Thermal Fatigue Life Prediction under Temperature Uncertainty for Shot Sleeve of Squeeze Casting Machine

Metals, 2021
To quantify the influence of temperature uncertainty on thermal fatigue life prediction of a shot sleeve in an injection mechanism, an uncertainty analysis method based on a Kriging surrogate model and Monte Carlo simulation (MCS) was proposed.
Dongdong You, Wenbin Pang, Dongqing Cai
doaj   +1 more source