Results 91 to 100 of about 1,410,709 (264)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Methods of left ventricle shape analysis in assessment and prediction of treatment effect in cardiac dyssynchrony

open access: yesРоссийский кардиологический журнал
The review discusses the importance of left ventricular shape analysis for diagnosis, severity assessment and prediction of treatment effectiveness in cardiac dyssynchrony.
R. O. Rokeakh   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Shape Analysis [PDF]

open access: yes, 2000
Reinhard Wilhelm   +2 more
openaire   +2 more sources

Quantifying the shape of nanoparticles: Segmentation and elongation measure

open access: yesZaštita Materijala, 2017
The influence of the shape of nanoparticles on the magnetic properties of nanoparticle materials is often mentioned, but is not much studied in literature. In order to better understand the magnetic properties of nanomaterials a very important step is to
Lazar Kopanja   +3 more
doaj   +1 more source

Compression for Smooth Shape Analysis

open access: yesCoRR, 2017
Most 3D shape analysis methods use triangular meshes to discretize both the shape and functions on it as piecewise linear functions. With this representation, shape analysis requires fine meshes to represent smooth shapes and geometric operators like normals, curvatures, or Laplace-Beltrami eigenfunctions at large computational and memory costs.
Virginia Estellers   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Property-Directed Shape Analysis [PDF]

open access: yes, 2014
This paper addresses the problem of automatically generating quantified invariants for programs that manipulate singly and doubly linked-list data structures. Our algorithm is property-directed–i.e., its choices are driven by the properties to be proven.
Itzhaky, Shachar   +4 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Home - About - Disclaimer - Privacy