Results 111 to 120 of about 2,321,763 (277)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Point‐PC: Point cloud completion guided by prior knowledge via causal inference
CAAI Transactions on Intelligence TechnologyThe goal of point cloud completion is to reconstruct raw scanned point clouds acquired from incomplete observations due to occlusion and restricted viewpoints.
Xuesong Gao +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2019 Presented as part of the Shape Machine Symposium on April 11, 2019 at 11:15 a.m. in the John & Joyce Caddell Building, Flex Space.James Park is a PhD Student in the School of Architecture at the Georgia Institute of Technology. His research investigates
Park, James
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Robotic Pick-and-Place With Uncertain Object Instance Segmentation and Shape Completion. [PDF]
IEEE Robot Autom Lett, 2021 Gualtieri M, Platt R.
europepmc +1 more source
The matrix completion problem [PDF]
, 2011 Nowadays, the relevant amount of information exchanges force the experts to create more reliable, secure and error-less devices through which these can happen.
Nalin, Gianmarco
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A brief psychometric test reveals robust shape completion deficits in schizophrenia that are less severe in bipolar disorder. [PDF]
Schizophr Res, 2022 Keane BP +3 more
europepmc +1 more source
3D Shape Completion with Multi-View Consistent Inference
, 2020 3D shape completion is important to enable machines to perceive the complete geometry of objects from partial observations. To address this problem, view-based methods have been presented.
Hu, Tao +2 more
core +1 more source