Results 141 to 150 of about 2,841,987 (371)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

THOR2: Topological Analysis for 3D Shape and Color‐Based Human‐Inspired Object Recognition in Unseen Environments

Advanced Intelligent Systems
Visual object recognition in unseen and cluttered indoor environments is a challenging problem for mobile robots. This study presents a 3D shape and color‐based descriptor, TOPS2, for point clouds generated from red green blue‐depth (RGB‐D) images and an
Ekta U. Samani, Ashis G. Banerjee
doaj   +1 more source

A Road Behavior Pattern-Detection Model in Querétaro City Streets by the Use of Shape Descriptors [PDF]

Antonio Trejo-Morales, Hugo Jiménez‐Hernández   +1 more
openalex   +1 more source

NodeSLAM: Neural Object Descriptors for Multi-View Shape Reconstruction [PDF]

, 2020
Edgar Sucar, Kentaro Wada, Andrew J. Davison   +2 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Diallel Analysis of Root Shape of Japanese Radish (Raphanus sativus L.) Based on Elliptic Fourier Descriptors.

, 2000
Hiroshi Iwata, Satoshi Niikura, Seiji Matsuura, Yasushi Takano, Yasuo Ukai   +4 more
openalex   +2 more sources

Beyond pixel-wise supervision for segmentation: A few global shape\n descriptors might be surprisingly good! [PDF]

, 2021
Hoel Kervadec, Houda Bahig, Laurent Létourneau‐Guillon, José Dolz, Ismail Ben Ayed   +4 more
openalex   +1 more source

Extending Shape Grammars with Descriptors [PDF]

, 2004
One of the problems in using shape grammars is being able to describe succinctly and precisely the conditions necessary to perform the appropriate transformation in a drawing. This paper proposes new descriptors in shape grammars that can control rule selection and the matching conditions between a schema and a drawing.
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source