Results 71 to 80 of about 514,857 (263)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Geometric analysis of investment casting turbine blades based on digital measurement data [PDF]
A turbine blade is one of the key components of the aero-engine. Its geometric shape should be inspected carefully in the production stage to ensure that it meets the tolerance specification. In the present paper, an approach for investment turbine blade
Cheng Yunyong, Wang Liya, Zhu Zhenzhen
doaj
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The Diagnostics and layout of railway track from the results of GPS measurements [PDF]
The diagnostics and layout of the railway track from the results of GPS measurements, possibilities and consideration of using the GPS technology in the railway geodesy. Integrating the GPS into the rail diagnostics and repairs technologies with focusing
Jaroslav Šíma, Ladislav Bitterer
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Mine-used pick wear measurement system based on shape from focus
For problems of complicated process, low accuracy and high cost in existing pick wear measurement methods, a mine-used pick wear measurement system based on shape from focus was designed. The collected sequence images of cone on top of pick are processed
LI Ning, DING Hua, WANG Yiliang
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Vison-Based 3D Shape Measurement System for Transparent Microdefect Characterization
The main task of vision-based industrial defect inspection is to implement efficient non-contact visual quality control, i.e., to detect if there is a defect and to achieve an accurate 3D shape measurement of such a defect, and this kind of vision defect
Yuanlong Deng +3 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

