Results 121 to 130 of about 130,134 (311)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Formal modelling of cognitive interpretation

open access: yes, 2007
We formally specify the interpretation stage in a dual state space human-computer interaction cycle. This is done by extending/reorganising our previous cognitive architecture.
Curzon, P   +3 more
core  

Some Issues of Biological Shape Modelling with Applications [PDF]

open access: yes, 2003
This paper illustrates current research at Informatics and Mathematical Modelling at the Technical University of Denmark within biological shape modelling.
Hans Henrik Thodberg   +17 more
core   +1 more source

Modelling of an irregular shape cargo allocated in open wagon [PDF]

open access: yesTransport Problems, 2009
The article gives the account of the results of calculation of stretches in flexible resilient elements of fastenings on the lower, inaccessible for pretwisting, irregular shape cargo section transported in an open wagon, depending upon initial value of ...
Elena TIMUKHINA
doaj  

Statistical Shape Modelling the In Vivo Location of Acetabular Wear in Retrieved Hip Implants. [PDF]

open access: yesBioengineering (Basel), 2022
Bergiers S   +9 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Analysing functional implications of differences in left ventricular morphology using statistical shape modelling. [PDF]

open access: yesSci Rep, 2022
Sophocleous F   +9 more
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Modelling shape memory alloys

open access: yes, 2003
Modelling shape memory alloys is based on choosing state quantities E which involve the phase volume fractions, on defining the free energy Ψ(E) and the pseudo-potential of dissipation Φ [E, dE/dt, grad T] depending on the thermal heterogeneity ...
C. Lexcellent   +5 more
core   +1 more source

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