Results 181 to 190 of about 38,612 (274)

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

open access: yesAngewandte Chemie International Edition, EarlyView.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp   +29 more
wiley   +1 more source

Terrestrial locomotion of microscopic robots enabled by 3D nanomembranes with nonreciprocal shape morphing. [PDF]

open access: yesProc Natl Acad Sci U S A
Wang Y   +17 more
europepmc   +1 more source

Magnetically encoded 3D mesostructure with high-order shape morphing and high-frequency actuation. [PDF]

open access: yesNatl Sci Rev, 2022
Li R   +12 more
europepmc   +1 more source

Procrustean pseudo‐landmark methods in Python to measure massive quantities of leaf shape data

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise When examining leaf shapes that are different from one another, it can be difficult to compare both the overall leaf shape and points along the leaf margin in biologically and statistically meaningful ways. Methods To address this problem, we present a simple and user‐friendly leaf shape analysis method in Jupyter Notebook and Python ...
Asia Hightower   +22 more
wiley   +1 more source

The tiger salamander as a promising alternative model organism to the axolotl for fracture healing and regenerative biology research

open access: yesThe Anatomical Record, EarlyView.
Abstract Scientists have been captivated by the ability to regenerate, focusing on uncovering the mechanisms of epimorphic regeneration and applying them to human medicine. The axolotl (Ambystoma mexicanum) has become the most intensively studied model in tetrapod regeneration research, particularly concerning limb regeneration.
Vivien Bothe, Nadia Fröbisch
wiley   +1 more source

Bioinspired hydrophobic pseudo-hydrogel for programmable shape-morphing. [PDF]

open access: yesNat Commun
Wang Z   +11 more
europepmc   +1 more source

A detailed redescription of a skeletally immature ‘Redondasaurus’ suggests ontogenetic transformations in the taxon mirror phytosaurian morphological evolution

open access: yesThe Anatomical Record, EarlyView.
Abstract The study of morphological evolution is fundamentally tied to ontogeny, yet studies of these heterochronic processes in the fossil record are rare. Fossils belonging to an ontogenetic series are difficult to assign to an ontogenetic stage due to inconsistent proxies for skeletal ages, challenging to taxonomically assign due to morphological ...
Erika R. Goldsmith, Michelle R. Stocker
wiley   +1 more source

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