Results 151 to 160 of about 336,617 (266)

Torsion angular bin strings: algorithmic update and additional validation. [PDF]

J Cheminform
Braun J, Lamei D, Hünenberger PH, Landrum GA, Riniker S.   +4 more
europepmc   +1 more source

Coarse Homotopy Theory and Shape Theory

This thesis establishes a connection between the coarse homotopy theory of Euclidean cones and the shape theory of compact metric spaces. For a compact metric space $X$, the coarse homotopy groups of the Euclidean cone $cX$ are determined by pointed shape invariants of $X$, fitting into a $\varprojlim^1$ sequence involving the Čech homotopy groups ...
openaire   +2 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Editorial: Culture and emotion in educational dynamics, volume V. [PDF]

Front Psychol
Riquelme E, Páez D, da Costa Dutra SC.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Understanding Curriculum Implementation with Entrustable Professional Activities Through the Lens of Normalization Process Theory. [PDF]

Perspect Med Educ
Hennus MP, Ladenheim RI, Chen HC, Chou FC, Hamstra SJ, Hennel EK, Marty AP, Romao GS, Yap M, Ten Cate O.   +9 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Intrinsic Correlation between Dynamic Phase Separation and Tunable Multishape Memory Effect in Double-Network Hydrogels. [PDF]

ACS Polym Au
Chen Z, Peng X, Wang X, Xing Z.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Toward feminist principles for epidemiology and public health. [PDF]

Front Public Health
Batram-Zantvoort S.
europepmc   +1 more source