Results 181 to 190 of about 437,550 (265)

Measuring what matters: governance challenges in defining follow-up priorities in complex healthcare systems. [PDF]

Health Res Policy Syst
Larsen T, Wikström E, Wijk H, Sawatzky R, Wolf A.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Impact of X-ray beam quality on organ-absorbed dose in chest CT: Evaluation using spectral analysis and beam-shaping filters. [PDF]

J Appl Clin Med Phys
Ito Y, Nishihara Y, Kobayashi M, Hibino T, Asada Y.   +4 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Negotiability of MB2 root canals using rotary or reciprocating systems: a randomized clinical trial. [PDF]

Braz Oral Res
Carpena LP, Araújo LP, Muniz FWMG, Ferreira NS.   +3 more
europepmc   +1 more source

Mapping the methanol-to-gasoline reaction in a fluidized bed reactor. [PDF]

RSC Adv
Filosa C, Askarli S, Alahmadi A, Navarro de Miguel JC, AlAbdullah M, Gallo JMR, Ruiz-Martinez J, Gascon J.   +7 more
europepmc   +1 more source