Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Shaping ability of 2Shape and NeoNiTi rotary instruments in preparation of curved canals using micro-computed tomography. [PDF]
Faisal I +3 more
europepmc +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
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Beyond S-cross section design: mechanical properties, metallurgical features and shaping ability of two nickel-titanium rotary instruments in double curved canals. [PDF]
Tres L +7 more
europepmc +1 more source
Comparison of shaping ability of the Reciproc Blue and One Curve with or without glide path in simulated S-shaped root canals. [PDF]
Biasillo V +8 more
europepmc +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Shaping ability of ProTaper Ultimate, ProTaper Gold, and Reciproc Blue in the mesiobuccal canals of maxillary first molars: a micro-computed tomography study. [PDF]
Yılmaz ÖS +4 more
europepmc +1 more source
A Comparative Study on the Shaping Ability and Cleaning Efficiency of Two Different Single-File Systems, Reciprocating Wave One Versus Continuous Rotation F360, Evaluated by Scanning Electron Microscope: An In Vitro Study. [PDF]
Samudrala A +7 more
europepmc +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
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