Results 31 to 40 of about 221,250 (263)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Energy-Aware Successor Tree Consistent EDF Scheduling for PCTGs on MPSoCs
IEEE AccessMultiprocessor System-on-Chips (MPSoCs) computing architectures are gaining popularity due to their high-performance capabilities and exceptional Quality-of-Service (QoS), making them a particularly well-suited computing platform for computationally ...
Umair Ullah Tariq +7 more
doaj +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Implementing Shared Memory Parallelism in MCBEND
EPJ Web of Conferences, 2017 MCBEND is a general purpose radiation transport Monte Carlo code from AMEC Foster Wheelers’s ANSWERS® Software Service. MCBEND is well established in the UK shielding community for radiation shielding and dosimetry assessments.
Bird Adam, Long David, Dobson Geoff
doaj +1 more source
An Abstraction Technique for Verifying Shared-Memory Concurrency
Applied Sciences, 2020 Modern concurrent and distributed software is highly complex. Techniques to reason about the correct behaviour of such software are essential to ensure its reliability.
Wytse Oortwijn +2 more
doaj +1 more source
Shared Memory Pipelined Parareal [PDF]
, 2017 For the parallel-in-time integration method Parareal, pipelining can be used to hide some of the cost of the serial correction step and improve its efficiency. The paper introduces a basic OpenMP implementation of pipelined Parareal and compares it to a standard MPI-based variant.
openaire +3 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Multigrain shared memory [PDF]
ACM Transactions on Computer Systems, 2000 Parallel workstations, each comprising tens of processors based on shared memory, promise cost-effective scalable multiprocessing. This article explores the coupling of such small- to medium-scale shared-memory multiprocessors through software over a local area network to synthesize larger shared-memory systems. We call these systems Distributed Shared-
Donald Yeung +2 more
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Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source