Results 71 to 80 of about 1,360,988 (290)

To Share or Not to Share: A Case for MPI in Shared-Memory

The evolution of parallel computing architectures presents new challenges for developing efficient parallelized codes. The emergence of heterogeneous systems has given rise to multiple programming models, each requiring careful adaptation to maximize performance.
Adam, Julien, Besnard, Jean-Baptiste, Roussel, Adrien, Jaeger, Julien, Carribault, Patrick, Pérache, Marc   +5 more
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Highly functional T-cell receptor repertoires are abundant in stem memory T cells and highly shared among individuals

Scientific Reports, 2017
To expand our knowledge of the ontogeny of the T-cell receptor (TCR) repertoire of antigen-specific T-cell subsets, we combined next-generation deep sequencing and single-cell multiplex clonotype analysis to evaluate the diversity and frequency of paired
Takahiko Miyama, Takakazu Kawase, Kazutaka Kitaura, Ren Chishaki, Masashi Shibata, Kumi Oshima, Hiroshi Hamana, Hiroyuki Kishi, Atsushi Muraguchi, Kiyotaka Kuzushima, Hiroh Saji, Tadasu Shin-I, Ryuji Suzuki, Tatsuo Ichinohe   +13 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Software patterns and data structures for the runtime coordination of robots, with a focus on real-time execution performance

Frontiers in Robotics and AI
This paper introduces software patterns (registration, acquire-release, and cache awareness) and data structures (Petri net, finite state machine, and protocol flag array) to support the coordinated execution of software activities (also called ...
Maria I. Artigas, Maria I. Artigas, Rômulo T. Rodrigues, Rômulo T. Rodrigues, Lars Vanderseypen, Herman Bruyninckx, Herman Bruyninckx, Herman Bruyninckx   +7 more
doaj   +1 more source

CaLRS: A Critical-Aware Shared LLC Request Scheduling Algorithm on GPGPU

The Scientific World Journal, 2015
Ultra high thread-level parallelism in modern GPUs usually introduces numerous memory requests simultaneously. So there are always plenty of memory requests waiting at each bank of the shared LLC (L2 in this paper) and global memory.
Jianliang Ma, Jinglei Meng, Tianzhou Chen, Minghui Wu   +3 more
doaj   +1 more source

Moving the shared memory closer to the processors: DDM [PDF]

, 1990
Multiprocessors with shared memory are considered more general and easier to program than message-passing machines. The scalability is, however, in favor of the latter.
Hagersten, Erik, Haridi, Seif, Landin, Anders   +2 more
core   +1 more source

And—or parallelism on shared-memory multiprocessors

The Journal of Logic Programming, 1993
Summary: The paper presents an extended and-or tree and an extended WAM ( Warren Abstract Machine) for efficiently supporting both and-parallel and or- parallel execution of logic programs on shared-memory multiprocessors. Our approach for exploiting both and- and or-parallelism is based on the binding-arrays method for or-parallelism and the RAP ...
Gopal Gupta 0001, Bharat Jayaraman
openaire   +2 more sources

Memory coherence in shared virtual memory systems [PDF]

ACM Transactions on Computer Systems, 1986
The memory coherence problem in designing and implementing a shared virtual memory on loosely coupled multiprocessors is studied in depth. Two classes of algorithms, centralized and distributed, for solving the problem are presented. A prototype shared virtual memory on an Apollo ring based on these algorithms has been implemented. Both theoretical and
Kai Li 0001, Paul Hudak
openaire   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source