Results 61 to 70 of about 633,274 (245)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Shared mobility - Novel insights on mode substitution patterns, trip and user characteristics

Journal of Cycling and Micromobility Research
With a growing number of shared mobility options, choosing not to own a car may become a new norm in the future. Shared mobility offers users a flexible range of low or zero-emission alternatives, potentially reducing the use of private cars, as well as ...
Gustav Bösehans, Margaret Carol Bell, Dilum Dissanayake   +2 more
doaj   +1 more source

Alleviating a form of electric vehicle range anxiety through On-Demand vehicle access [PDF]

, 2013
On-demand vehicle access is a method that can be used to reduce types of range anxiety problems related to planned travel for electric vehicle owners. Using ideas from elementary queueing theory, basic QoS metrics are defined to dimension a shared fleet ...
Griggs, Wynita, King, Christopher, Quinn, Karl, Shorten, Robert, Wirth, Fabian   +4 more
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

A Study on the Key Factors for the Sustainable Development of Shared Mobility Based on TDM Theory: The Case Study from China

Systems
This study is based on an investigation of shared mobility in Chinese cities, which identifies the factors affecting the sustainable development of shared mobility based on the theoretical framework of TDM (travel demand management). Through a literature
Min Wang, Qiaohe Zhang, Jinqi Hu, Yixuan Shao   +3 more
doaj   +1 more source

Balancing Affordability and Opportunity: An Evaluation of Affordable Homeownership Programs With Long-Term Affordability Controls [PDF]

, 2010
Examines seven shared equity programs that allow low-income families to purchase homes at below-market prices with resale restrictions and their outcomes in terms of preserving affordability, personal wealth creation, security of tenure, and ...
Brett Theodos, David Price, Kenneth Temkin   +2 more
core  

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Shared mobility beyond urban limits: Insights on usage in two rural towns in Austria

Sustainable Futures
Today, shared mobility has been widely introduced and promoted in urban areas as an alternative solution for more sustainable travel. At the same time, the potential of shared mobility in smaller cities and rural areas, where the majority of people live ...
Julia Schilder, Juliane Stark, Reinhard Hössinger, Yusak Susilo   +3 more
doaj   +1 more source

Evaluation of a Novel Electric Health Record Sidecar Application to Display Rheumatoid Arthritis Clinical Outcomes During Clinic Visits: Results of a Stepped‐Wedge Cluster Randomized Pragmatic Trial

Arthritis Care &Research, EarlyView.
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk, Jing Li, Cathy Nasrallah, Cherish Wilson, Alicia Hamblin, Christine Hariz, Cammie Young, Stephen Shiboski, Emma Kersey, Mary Nakamura, Judith F. Ashouri, Mehrdad Matloubian, Andrew J. Gross, Jennifer Barton, Beth Berrean, Jonathan Prugh, Jinoos Yazdany   +16 more
wiley   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

Arthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King, Alanna Weisman, Baiju R. Shah, Robert Goldberg, Amish Parikh, Ian Stanaitis, Vivian Hung, Rosane Nisenbaum, Abdalmohsen Almodahka, Lorraine Lipscombe, Gillian A. Hawker   +10 more
wiley   +1 more source