Results 71 to 80 of about 77,286 (258)
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Shared Satisfaction among Residents Living in Multiracial Neighborhoods
Social Problems, 2022 Abstract Multiracial neighborhood integration has become more common in U.S. metropolitan areas over the past three decades. This article takes up the question: are residents satisfied living in multiracial neighborhoods? Traditional theories of racial change predict low levels of satisfaction in these neighborhoods, while newer studies ...
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Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
L’architecture et les arts décoratifs au service de l’éducation nationale italienne
MDCCC 1800, 2013 The paper aims to describe the process that links architecture and decorative arts with an educational role in Italy before and after the country’s unity.
Dellapiana, Elena
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New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
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Factors Affecting First and Second Birth Intervals among 15-49 Year-Old Women in Tehran
مجله اپیدمیولوژی ایران, 2019 Background and Objectives: One of the most important determinants of the fertility level is the birth interval. Considering the importance of this issue, the aim of this study was to analyze the first and second birth intervals using shared frailty ...
A Bagheri, M Saadati
doaj
A user study on electric shared mobility for residents
, 2021 This study aims at developing better understanding of the requirements on an offering of electric Shared Mobility for Residents (eSMfR) in order to make it attractive from the resident’s point of view. The study has been based on interaction with randomly recruited residents in a couple of Swedish communities.
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source