Results 41 to 50 of about 296,068 (343)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Tax preferences, dividends and lobbying for maximum value

open access: yesSouth African Journal of Economic and Management Sciences, 2017
Background: The value of equity investments depends to some extent on the tax consequences for investors. When groups of investors have different tax preferences, this can lead to conflicting pressures on firms to either retain earnings or pay dividends.
Wessel M. Badenhorst
doaj   +1 more source

Exploring the rationale of enlightened shareholder value in the realm of UK company law – the path dependence perspective [PDF]

open access: yes, 2011
Despite conventional beliefs in the predominance of shareholder value, a broader agenda of stakeholder consideration has been advocated in the UK by the recently-introduced ESV principle – the overriding corporate objective in the new company law regime.
Wen, S, Zhao, J
core   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Features governance of the company from board of directors

open access: yesСтратегические решения и риск-менеджмент, 2017
This paper considers the features of corporate management on the part of board of directors. This paper includes consideration of efficiency of decision-making, the resolution of conflicts be-tween shareholders, realizations of investment in the company.
S. I. Lutsenko
doaj   +1 more source

Structural Analysis of Projected Networks of Shareholders and Stocks Based on the Data of Large Shareholders’ Shareholding in China’s Stocks

open access: yesMathematics, 2023
This paper establishes a shareholder-stock bipartite network based on the data of large shareholders’ shareholding in the Shanghai A-share market of China in 2021.
Ruijie Liu, Yajing Huang
doaj   +1 more source

Corporate Political Spending: Why Shareholders Must Weigh In [PDF]

open access: yes, 2012
This article focuses upon the growing problem confronting companies and their shareholders: the use of general treasury (i.e., shareholder money) to propagate political agendas which are not only contrary to companies’ policies of employment, but are ...
Goodridge, Julie N.W., Jantz, Christine
core   +1 more source

Bone‐Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation

open access: yesAdvanced Healthcare Materials, EarlyView.
A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker   +5 more
wiley   +1 more source

SHAREHOLDER PARTICIPATION IN ANNUAL GENERAL MEETINGS UNDER NIGERIAN CORPORATE LAW: PHILOSOPHY, PRACTICE AND THE ROLE OF SHAREHOLDER ASSOCIATIONS

open access: yesUUM Journal of Legal Studies, 2020
Shareholders and board of directors in an annual general meeting (AGM) are the two organs of a company. Shareholders are legally empowered to participate in the AGM to meet directors and know about the performance of the company.
Shamsuddeen Magaji   +2 more
doaj   +5 more sources

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