Results 51 to 60 of about 285,672 (343)
Advanced Materials, EarlyView.This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle +9 more
wiley +1 more source
Valuation implications of pharmaceutical companies' R&D regulatory approval notifications [PDF]
, 2013 This paper examines shareholder wealth effects surrounding applications to, and approvals by, the United States Food and Drug Administration (FDA) for firms listed on the New York (NYSE) and London (LSE) stock exchanges.
Hamill, P.A., McIlkenny, P., Opong, K.K.
core +1 more source
Advanced Materials Interfaces, EarlyView.This study investigates how the mode of application affects drug delivery from coated microneedles. Combining finite element modeling with custom 3D‐printed Franz Diffusion Cells, the researchers found that prolonged application pressure from microneedles in situ reduces drug permeation.
Wenting Shu +5 more
wiley +1 more source
Exploring the rationale of enlightened shareholder value in the realm of UK company law – the path dependence perspective [PDF]
, 2011 Despite conventional beliefs in the predominance of shareholder value, a broader agenda of stakeholder consideration has been advocated in the UK by the recently-introduced ESV principle – the overriding corporate objective in the new company law regime.
Wen, S, Zhao, J
core +1 more source
State Ownership and Corporate Governance [PDF]
, 2011 State ownership of publicly-traded corporations remains pervasive around the world, and has been increasing in recent years. Existing literature focuses on the implications of government ownership for corporate governance and performance at the firm ...
Pargendler, Mariana
core +4 more sources
Advanced Science, EarlyView.ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen +17 more
wiley +1 more source
Tax preferences, dividends and lobbying for maximum value
South African Journal of Economic and Management Sciences, 2017 Background: The value of equity investments depends to some extent on the tax consequences for investors. When groups of investors have different tax preferences, this can lead to conflicting pressures on firms to either retain earnings or pay dividends.
Wessel M. Badenhorst
doaj +1 more source
A Little Birdie Said: How Twitter is Disrupting Shareholder Activism [PDF]
, 2015 Shareholders are organizing and mobilizing on new social media platforms like Twitter. This changes the dynamics of shareholder proxy contests in ways that favor shareholders over management. Disruptive technology may bring about a shareholder revolution,
Oranburg, Seth C.
core +1 more source
Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells
Advanced Science, EarlyView.Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser +20 more
wiley +1 more source
UUM Journal of Legal Studies, 2020 Shareholders and board of directors in an annual general meeting (AGM) are the two organs of a company. Shareholders are legally empowered to participate in the AGM to meet directors and know about the performance of the company.
Shamsuddeen Magaji +2 more
doaj +3 more sources