Results 241 to 250 of about 224,835 (308)

Axatilimab Immunogenicity and Clinical Relevance in Patients with Chronic Graft‐Versus‐Host Disease

Clinical Pharmacology &Therapeutics, EarlyView.
Axatilimab, a monoclonal antibody targeting colony‐stimulating factor 1 (CSF‐1) receptor, is approved in the US for the treatment of chronic graft‐versus‐host disease (cGVHD) after failure of ≥2 lines of systemic therapy. In this study, the effects of antidrug antibody (ADA) status on the pharmacokinetics, pharmacodynamics, efficacy, and safety of ...
Yan‐ou Yang, Xing Liu, Breann Barker, Xuecheng Zhang, Peter Ordentlich   +4 more
wiley   +1 more source

Impact of excessive environmental information disclosure on stock price crash risk. [PDF]

PLoS One
Dong G, Ma G.
europepmc   +1 more source

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

Clinical Pharmacology &Therapeutics, EarlyView.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout, Stefan De Buck, Jacques Gaudreault, Sébastien Jolivet, Vincent Duval, Valérie Cosson, Marie‐Laure Delporte   +6 more
wiley   +1 more source

Benefit of Semaglutide in Symptomatic Peripheral Artery Disease by Baseline Type 2 Diabetes Characteristics: Insights From STRIDE, a Randomized, Placebo-Controlled, Double-Blind Trial. [PDF]

Diabetes Care
Rasouli N, Guder Arslan E, Catarig AM, Houlind K, Ludvik B, Nordanstig J, Sourij H, Thomas S, Verma S, Bonaca MP.   +9 more
europepmc   +1 more source

Balancing evidence and individualization in adjuvant CDK4/6 therapy. [PDF]

Transl Cancer Res
Al-Shamsi HO, Oner M, Mokbel K.
europepmc   +1 more source

From union clout to corporate couture: Unveiling the impact of trade unions on corporate social responsibility. [PDF]

PLoS One
Mandliya A, Pandey J, Sohani SS, Sheikh RA.   +3 more
europepmc   +1 more source

Context matters: evaluating AI-assisted chest radiograph interpretation in military field hospitals. [PDF]

Trauma Surg Acute Care Open
Callcut RA.
europepmc   +1 more source

Controlling shareholders' share pledge and share repurchase notices of listed companies. [PDF]

PLoS One
Cao L, Zhu X, Xie J.
europepmc   +1 more source

Quantum speedup for nonreversible Markov chains. [PDF]

Nat Commun
Claudon B, Piquemal JP, Monmarché P.
europepmc   +1 more source

Validating the biological origin of in vivo fractional intracellular volume from VERDICT-MRI in the prostate

Masramon M, Mathew M, Singh S, Mertzanidou T, Clemente J, Retter A, Thorley N, Phipps A, Parry T, Papoutsaki M, Smith L, Grussu F, Kasivisvanathan V, Grey A, Dinneen E, Shaw G, Patel D, Caselton L, Moore CM, Atkinson D, Haider A, Freeman A, Alexander DC, Punwani S, Panagiotaki E.   +24 more
europepmc   +1 more source