Results 301 to 310 of about 11,116,898 (377)

Power, choice, exposure and fragility: Reframing fairness in equity for the corporate and insolvency sphere

open access: yesInternational Insolvency Review, EarlyView.
Abstract Where is the place of humanity in current corporate and insolvency frameworks and their theoretical underpinning? How can it be assured that the institutions that have been invented through human ingenuity and brilliance serves the collective human experience fully and equitably? Insolvency law has long been theoretically conceptualised on the
Jennifer L. L. Gant
wiley   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner   +3 more
wiley   +1 more source

Inhibition of autotaxin activity with IOA‐289 decreases fibrosis in mouse E0771 breast tumors

open access: yesInternational Journal of Cancer, Volume 157, Issue 6, Page 1205-1217, 15 September 2025.
What's new? Lysophosphatidate is one of the critical mediators of fibrosis formation in the tumor microenvironment, which hinders immune surveillance and therapy. Building on their previous finding that blocking lysophosphatidate production with the autotaxin inhibitor, IOA‐289 decreased tumor growth by approximately 60%, here the authors show that ...
Xiaoyun Tang   +4 more
wiley   +1 more source

Shareholder Value - nur ein Schlagwort? [PDF]

open access: yes, 2010
Härtel, Hans-Hagen
core  

Real‐world study on fluoropyrimidine‐related toxicity outcomes in cancer patients with select DPYD variant alleles that received DPYD genotype‐guided dosing

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Fluoropyrimidines, a key component of chemotherapy regimens for a variety of solid tumors, can cause severe toxicity. Patients who have specific genetic variants in the DPYD gene, which encodes an enzyme that inactivates fluoropyrimidines, have increased susceptibility to this toxicity.
Sofía L. J. Peeters   +12 more
wiley   +1 more source

Final analysis of ArtemisR, a European real-world retrospective study of apalutamide for the treatment of patients with metastatic hormone-sensitive prostate cancer. [PDF]

open access: yesBMC Cancer
Boegemann M   +15 more
europepmc   +1 more source

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