Results 61 to 70 of about 349,708 (249)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Legal problems in public-private property interactions within entrepreneurship
The nature of contemporary entrepreneurial relations among market participants is significantly shaped by Russia’s mixed economy. This article argues for re-evaluation constitutional foundations of the Russian economic system within the Civil Code of the
Vladimir K. Andreev, Vasiliy A. Laptev
doaj +1 more source
This article tries to analyse the impact of changes in the USD/EUR exchange rate on the return of stock indexes. We deal with investments on the American and on the European stock market made by European investors (investing in EUR) and by American ...
Oldřich Rejnuš, Oldřich Šoba
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
This repository hosts the slides and other materials related to my presentation at 2018 ICCSET a conference hosted by Universitas Muria Kudus. I created the slides using Jupyter Notebook, hence click index.ipynb file to read the slides.Direct link to Github: https://github.com/dasaptaerwin ...
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
DEVELOPMENT PROBLEMS OF JOINT STOCK COMPANIES IN RUSSIA
The problems on th e origin and development of the joint stock companies in Russia are considered. Their form ation, shortcomings and challenges are characterized, the ways of improving their work are outlined t hrough the example of ‘Rostvertol’ JSC.
Vladimir I. Budarin
doaj

