Results 11 to 20 of about 55,620 (193)

Anatomy, feeding ecology, and ontogeny of a transitional baleen whale: a new genus and species of Eomysticetidae (Mammalia: Cetacea) from the Oligocene of New Zealand [PDF]

open access: yesPeerJ, 2015
The Eocene history of cetacean evolution is now represented by the expansive fossil record of archaeocetes elucidating major morphofunctional shifts relating to the land to sea transition, but the change from archaeocetes to modern cetaceans is poorly ...
Robert W. Boessenecker, R. Ewan Fordyce
doaj   +2 more sources

Multi-parameter average strain energy density factor criterion applied on the sharp material inclusion problem

open access: yesProcedia Structural Integrity, 2018
Abstract The tip of a sharp material inclusion (SMI) embedded in a parent material is considered as the singular stress concentrator. The SMI tip is modelled as a special case of a multi-material junction. The singular stress behaviour is caused by the material mismatch and geometrical discontinuity. The power of singularity is lower in comparison to
Ondřej Krepl, Jan Klusák
openaire   +1 more source

Ultra-high resolution X-ray structure of orthorhombic bovine pancreatic Ribonuclease A at 100K

open access: yesBMC Chemistry, 2023
The crystal structure of orthorhombic Bovine Pancreatic Ribonuclease A has been determined to 0.85 Å resolution using low temperature, 100 K, synchrotron X-ray data collected at 16000 keV (λ = 0.77 Å). This is the first ultra-high-resolution structure of
David R. Lisgarten   +9 more
doaj   +1 more source

Influence of disease activity and treatment on rate of joint destruction in rheumatoid arthritis

open access: yesНаучно-практическая ревматология, 2008
Severity of hands and feet joint destruction is the most objective marker of rheumatoid arthritis (RA) progression determining functional disability. The main aim of RA treatment is suppression of joint destruction. Objective.
D V Goryachev   +4 more
doaj   +1 more source

The value of “constant sharpness” as a diagnostic sign in MR-Mammography

open access: yesEuropean Journal of Radiology Open, 2016
Purpose: To examine “constant lesion sharpness” as a morphological diagnostic sign in the differential diagnosis between benign and malignant lesions.
Clemens G. Kaiser, M.D.   +6 more
doaj   +1 more source

“Every collective farmer must become a fighter for a bountiful harvest”: nursery services for the rural population of Penza region during the Great Patriotic War

open access: yesИзвестия высших учебных заведений. Поволжский регион: Гуманитарные науки, 2023
Background. The current demographic situation in Russia requires the urgent implementation of diverse measures to support families with children. Among them, ensur-ing a sufficient number of places in kindergartens, nurseries and medical institutions is ...
I.N. Inozemtsev, V.N. Parshina
doaj   +1 more source

Kaarel Irdi repertuaaripoliitilised vaated Vanemuise teatri juhina. Kaarel Ird’s Repertoire Policy as Manager of the Vanemuine Theatre

open access: yesMethis: Studia Humaniora Estonica, 2011
This article focuses on the meaning of ’repertoire policy’, which in a broader sense usually means the conformity of someone’s creative activities with their main target groups and the interests and expectations of these target groups.
Jaak Viller
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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