Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley +1 more source
Contemporary Methods for Capturing Juvenile Salmonids in the Marine Environment
ABSTRACT Anadromous salmonids play vital roles in marine and freshwater ecosystems. The most abundant of these fishes—Pacific salmon (Oncorhynchus spp.)—are integral to coastal ecosystems and communities across the North Pacific Rim, but numerous populations are experiencing dramatic declines, particularly towards the south of their range.
Sean C. Godwin +6 more
wiley +1 more source
Interstage market spillovers of the photovoltaic industry chain in China. [PDF]
Wang J, Li L, Shen T.
europepmc +1 more source
The Role of Intangible Investment in Predicting Stock Returns: Six Decades of Evidence
ABSTRACT Using an intangible intensity factor that is orthogonal to the Fama–French factors, we compare the role of intangible investment in predicting stock returns over the periods 1963–1992 and 1993–2022. For 1963–1992, intangible investment is weak in predicting stock returns, but for 1993–2022, the predictive power of intangible investment becomes
Lin Li
wiley +1 more source
Product Market Threats and Leases
ABSTRACT We document robust evidence of increased corporate leasing in the presence of product market threats. This finding is robust to a battery of tests exploiting plausibly exogenous variation in product market threats to address the potentially endogenous nature of leasing and product markets, including Chinese import penetration, the granting of ...
Douglas (D. J.) Fairhurst +3 more
wiley +1 more source
An Automated Decision Support System for Portfolio Allocation Based on Mutual Information and Financial Criteria. [PDF]
Kaucic M, Pelessoni R, Piccotto F.
europepmc +1 more source
Application of regularized covariance matrices in logistic regression and portfolio optimization. [PDF]
Sun F, Huang X.
europepmc +1 more source
Abstract Cardiac afferent neurons have been shown to trigger overactivation of neurohormonal systems known to drive adverse cardiac remodeling following myocardial infarction (MI). Acid‐sensing ion channels (ASICs) that are highly expressed in cardiac sympathetic afferents sense ischemia‐induced myocardial acidosis.
Karley M. Monaghan +14 more
wiley +1 more source
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Homologous): homologous rodent models. [PDF]
Burns KA +18 more
europepmc +1 more source
PyPortOptimization: A portfolio optimization pipeline leveraging multiple expected return methods, risk models, and post-optimization allocation techniques. [PDF]
Nakhate R, Ramachandran H, Mahajan A.
europepmc +1 more source

