Results 251 to 260 of about 836,502 (333)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Automatic respiratory and bulk patient motion corrected (ACROBATIC) free-running whole-heart five-dimensional magnetic resonance imaging. [PDF]

J Cardiovasc Magn Reson
Ferincz R, Prša M, Tenisch E, Yerly J, Roy CW.   +4 more
europepmc   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

A Closer Look at Dowling-Degos Disease: A Case Report and Quantitative Assessment of Its Surface Texture Parameters. [PDF]

Cureus
Sollitto CF, Wolinsky C, Beatty BL.
europepmc   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht, Lukas Meyer, Gabriel Broocks, Matthias Bechstein, Christian Thaler, Christian Heitkamp, Laurens Winkelmeier, Vincent Geest, Alexander Heitkamp, Maximilian Jungnitz, Gregor Peter, Luca Meucci, Tobias Faizy, Jawed Nawabi, Caspar Brekenfeld, Fabian Flottmann, Maximilian Schell, Alexandros Hadjilaou, Uta Hanning, Götz Thomalla, Jens Fiehler, Susanne Gellißen, Helge C. Kniep, for the German Stroke Registry Endovascular Treatment, (GSR‐ET) Alexander Nave, Anna Alegiani, Annerose Mengel, Arno Reich, Bernd Eckert, Charlotte Pietrock, Christian Nolte, Eberhard Siebert, Fabian Flottmann, Fee Keil, Franziska Dorn, Gabor Petzold, Götz Thomalla, Hanna Zimmermann, Jan Borggrefe, Jan Hendrik Schäfer, Jens Fiehler, Joachim Röther, Klaus Gröschel, Lars Kellert, Mario Abruscato, Maximilian Schell, Omid Nikoubashman, Peter Schellinger, Silke Wunderlich, Steffen Tiedt, Sven Thonke, Timo Uphaus, Tobias Boeckh‐Behrens, Ulrike Ernemann   +53 more
wiley   +1 more source

Respiratory Motion-Corrected Model-Based 3D Water-Fat MRA of the Thorax at 0.55 T. [PDF]

Magn Reson Med
Stoll R, Kolbitsch C, Schmidt M, Nickel MD, Schaeffter T, Giese D.   +5 more
europepmc   +1 more source

Automatic Respiratory and Bulk Patient Motion Corrected 3D Fetal MRI. [PDF]

Magn Reson Med
Ferincz R, Alamo L, Secinaro A, Tenisch E, Bustin A, Piccini D, Prša M, Yerly J, Roy CW.   +8 more
europepmc   +1 more source

Sharper, straighter, stiffer, stronger: sexually dimorphic bill shape enhances male stabbing performance in the green hermit hummingbird (Phaethornis guy). [PDF]

J Exp Biol
Garzón-Agudelo F, Mansfield L, Epperly K, Rico-Guevara A.   +3 more
europepmc   +1 more source

Clinical validation of comprehensive time- and frequency-domain photoplethysmography features from a single-sensor system for non-invasive assessment of vascular load and systolic blood pressure. [PDF]

Front Physiol
Lin CN, Chang CP, Lin JJ, Chang JN, Hung YC, Ko PY.   +5 more
europepmc   +1 more source

Segment-Based Signal Typing and Predictive Modeling in Pediatric Dysphonia With Different Vibratory Sources. [PDF]

J Speech Lang Hear Res
Park Y, Anand S, Brehm SB, Kelchner L, Weinrich B, Shrivastav R, de Alarcon A, Eddins DA.   +7 more
europepmc   +1 more source