Results 21 to 30 of about 1,474,305 (299)
EEG for Diagnosis of Autism Spectrum Disorder
Pediatric Neurology Briefs, 2018 Investigators from Boston University and the University of San Francisco evaluated whether EEG could be reliably used as an early biomarker for diagnosis of autism spectrum disorder.
Meghan O'Neill, Talia Shear
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Anisotropic shear melting and recrystallization of a two-dimensional complex (dusty) plasma
, 2013 A two-dimensional plasma crystal was melted by suddenly applying localized shear stress. A stripe of particles in the crystal was pushed by the radiation pressure force of a laser beam.
Ivlev, A. V. +2 more
core +1 more source
Vascular adaptation model from force balance: Physarum polycephalum as a case study
New Journal of Physics, 2023 Understanding vascular adaptation, namely what drives veins to shrink or grow, is key for the self-organization of flow networks and their optimization.
Sophie Marbach, Noah Ziethen, Karen Alim
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Crossover between Equilibrium and Shear-controlled Dynamics in Sheared Liquids
, 2002 We present a numerical simulation study of a simple monatomic Lennard-Jones liquid under shear flow, as a function of both temperature and shear rate.
B. Coluzzi +22 more
core +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Orientation of plastic rearrangements in two-dimensional model glasses under shear
, 2018 The plastic deformation of amorphous solids is mediated by localized shear transformations involving small groups of particles rearranging irreversibly in an elastic background.
Nicolas, Alexandre, Rottler, Jörg
core +2 more sources
Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma +9 more
wiley +1 more source