Results 21 to 30 of about 311,014 (268)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Strong gravitational lensing’s ‘external shear’ is not shear
Monthly Notices of the Royal Astronomical SocietyABSTRACT The distribution of mass in galaxy-scale strong gravitational lenses is often modelled as an elliptical power-law plus ‘external shear’, which notionally accounts for neighbouring galaxies and cosmic shear along our line of sight.
Amy Etherington +22 more
openaire +6 more sources
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
Advanced Engineering Materials, EarlyView.This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Flexible Shear and Normal Force Sensor Using only One Layer of Polyvinylidene Fluoride Film
Applied Sciences, 2019 We have proposed a flexible sensor that can sense shear and normal forces, and can be fabricated through a simple process using only one layer of polyvinylidene fluoride (PVDF) film.
Ye Rim Lee +3 more
doaj +1 more source
Shear Modulus and Shear-Stress Fluctuations in Polymer Glasses [PDF]
Physical Review Letters, 2017 5 pages, 6 figure, published at ...
Kriuchevskyi, I. +3 more
openaire +3 more sources