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Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng +16 more
wiley +1 more source
Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
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Shear behavior of human skull bones
Journal of the Mechanical Behavior of Biomedical Materials, 2021A shear-punch test (SPT) experimental method was developed to address the lack of shear deformation and failure response data for the human skull as a function of local bone microarchitecture. Improved understanding of skull deformation and fracture under varying stress-states helps implement mechanism-based, multi-axial material models for finite ...
A D, Brown +2 more
openaire +2 more sources
Marine georesources & geotechnology, 2021
In offshore engineering, the soft marine clay beneath an embankment may be subjected to anisotropic consolidation stress paths, which greatly affect its monotonic and post-cyclic shear behavior.
M. Dai +3 more
semanticscholar +1 more source
In offshore engineering, the soft marine clay beneath an embankment may be subjected to anisotropic consolidation stress paths, which greatly affect its monotonic and post-cyclic shear behavior.
M. Dai +3 more
semanticscholar +1 more source
Bolted shear connectors in steel–concrete composite structures: Shear behavior
Structures, 2023The use of bolted shear connectors is of great importance to the sustainable development of steel–concrete composite structures. In this paper, an experimental program consisting of four push-out specimens is performed to investigate the effects of bolt length and fabrication method of concrete slabs on the shear behavior of single-nut embedded bolted ...
Xiaoyang Liu +9 more
openaire +2 more sources
, 2021
This study numerically investigated the shear behavior of novel composite shear connectors, which consisted of grouped head studs embedded in high-strength concrete-filled (HSC-filled) she...
Shaodi Wang +4 more
semanticscholar +1 more source
This study numerically investigated the shear behavior of novel composite shear connectors, which consisted of grouped head studs embedded in high-strength concrete-filled (HSC-filled) she...
Shaodi Wang +4 more
semanticscholar +1 more source
Elevated Temperature Effects on Geotextile–Geomembrane Interface Shear Behavior
Journal of Geotechnical and Geoenvironmental Engineering, 2021The performance of geosynthetic layered systems during their service life in terms of interface shear behavior and strength properties is of major importance in certain geotechnical applica...
T. Karademir, J. D. Frost
semanticscholar +1 more source
Experimental Study on Shear Behavior and a Revised Shear Strength Model for Infilled Rock Joints
International Journal of Geomechanics, 2020To better understand the shear behavior of infilled rock joints with standard joint roughness coefficient (JRC) profiles, direct shear experiments are performed on sand and clay infilled j...
Yanlin Zhao +5 more
semanticscholar +1 more source
“Unexpected” shear‐wave behavior
GEOPHYSICS, 1997In a previous study, we inverted shear‐wave birefringence observations from an azimuthal vertical seismic profile (VSP) experiment conducted at the Conoco Borehole Test Facility, Oklahoma (Horne and MacBeth, 1994; Horne, 1995). Our results indicate that the observations can be interpreted in terms of two distinctly different transversely isotropic (TI)
Steve Horne, Colin MacBeth, Enru Liu
openaire +1 more source

