Results 31 to 40 of about 72,618 (295)

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Analysis of the Direct Shear Test and Microstructure of the Lunar Soil Simulant Solidified by Sodium Silicate

Advances in Materials Science and Engineering, 2022
The lunar soil is an ideal building material for future lunar base construction. In order to improve the strength of lunar soil, basalt with similar composition to lunar soil was used to simulate lunar soil due to lack of real lunar soil, and the ...
Qinyong Ma, Hanyan Wang
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Deformation and cyclic resistance of sand in large-strain undrained torsional shear tests with initial static shear stress

Soils and Foundations, 2021
This paper presents the findings from an experimental study focusing on the undrained cyclic behavior of sand in the presence of initial static shear stress.
Muhammad Umar, Gabriele Chiaro, Takashi Kiyota, Nazish Ullah   +3 more
doaj  

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

A refined shear deformation theory for flexure of thick beams

Latin American Journal of Solids and Structures
A Hyperbolic Shear Deformation Theory (HPSDT) taking into account transverse shear deformation effects, is used for the static flexure analysis of thick isotropic beams. The displacement field of the theory contains two variables.
Yuwaraj M. Ghugal, Rajneesh Sharma
doaj   +1 more source

Numerical Studies of Influencing Factors on the Homogeneity of the Powder Mixture during the Powder Spreading Process of Powder Bed Fusion–Laser Beam/Metal

Advanced Engineering Materials, EarlyView.
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng, Ziping Sang, Jiali Zhang, Felix Radtke, Louis Becker, Simone Herzog, Sebastian Weber, Christoph Broeckmann   +7 more
wiley   +1 more source

Shear deformation laminate theory used for sandwiches [PDF]

Metalurgija, 2011
The shear deformation laminate theory is very useful for the calculation of the sandwich composites. Sandwich can be defined as a special laminate with three layers and therefore can be modeled using shear deformation laminate theory by neglecting of ...
E. Kormaníková, Ilija Mamuzić
doaj  

Superconductivity in Compression-Shear Deformed Diamond

Physical Review Letters, 2020
Diamond is a prototypical ultrawide band gap semiconductor, but turns into a superconductor with a critical temperature T_{c}≈4  K near 3% boron doping [E. A. Ekimov et al., Nature (London) 428, 542 (2004)NATUAS0028-083610.1038/nature02449]. Here we unveil a surprising new route to superconductivity in undoped diamond by compression-shear deformation ...
Chang Liu, Xianqi Song, Quan Li, Yanming Ma, Changfeng Chen   +4 more
openaire   +5 more sources