Results 41 to 50 of about 243,546 (314)

Investigation of spiral blood flow in a model of arterial stenosis [PDF]

open access: yes, 2009
The spiral component of blood flow has both beneficial and detrimental effects in human circulatory system [Stonebridge PA, Brophy CM. Spiral laminar flow in arteries? Lancet 1991; 338: 1360–1].
Paul, M.C., Larman, A.
core   +1 more source

Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes

open access: yesBiology, 2021
Ex vivo culture conditions during the manufacturing process impact the therapeutic effect of cell-based products. Mimicking blood flow during ex vivo culture of monocytes has beneficial effects by preserving their migratory ability.
Elisa Wirthgen   +4 more
doaj   +1 more source

Numerical Simulations of Red-Blood Cells in Fluid Flow: A Discrete Multiphysics Study

open access: yesChemEngineering, 2021
In this paper, we present a methodological study of modelling red blood cells (RBCs) in shear-induced flows based on the discrete multiphysics (DMP) approach.
Amin Rahmat   +3 more
doaj   +1 more source

Detachment Energy Evaluation in Nano-Particle Cleaning Using Lateral Force Microscopy

open access: yesApplied Sciences
It has been difficult to detach abrasive particles smaller than 50 nm from polished surfaces in post-CMP cleaning. During the cleaning process, the residual nano-particles exert shear force in the inevitable shear flow.
Yutaka Terayama   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Electroosmotic shear flow in microchannels [PDF]

open access: yesJournal of Colloid and Interface Science, 2013
We generate and study electroosmotic shear flow in microchannels. By chemically or electrically modifying the surface potential of the channel walls a shear flow component with controllable velocity gradient can be added to the electroosmotic flow caused by double layer effects at the channel walls.
Mampallil Augustine, Dileep   +1 more
openaire   +2 more sources

Mean flow of turbulent–laminar patterns in plane Couette flow [PDF]

open access: yes, 2007
A turbulent–laminar banded pattern in plane Couette flow is studied numerically. This pattern is statistically steady, is oriented obliquely to the streamwise direction, and has a very large wavelength relative to the gap. The mean flow, averaged in time
DWIGHT BARKLEY   +3 more
core   +1 more source

Order and density fluctuations near the boundary in sheared dense suspensions

open access: yesFrontiers in Physics, 2022
We introduce a novel approach to reveal ordering fluctuations in sheared dense suspensions, using line scanning in a combined rheometer and laser scanning confocal microscope. We validate the technique with a moderately dense suspension, observing modest
Joia M. Miller   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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