Results 191 to 200 of about 29,832 (302)

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, restores blood–brain barrier integrity in a human stem cell‐based model of ischaemic stroke

open access: yesBritish Journal of Pharmacology, EarlyView.
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó   +14 more
wiley   +1 more source

Topology‐based Visual Analysis of Hydrothermal Plumes

open access: yesComputer Graphics Forum, EarlyView.
Abstract Hydrothermal plumes are turbulent structures of intense heat and mineral smoke that rise and disperse into the deep ocean. Existing models generally characterize these systems as a single axisymmetric plume originating from a point source. However, this assumption breaks down in weakly venting, spatially distributed systems, where low‐flux ...
Adhitya Kamakshidasan   +3 more
wiley   +1 more source

Dynamic Wave Trains: A Procedural Approach to Spatially Varying Ocean Synthesis

open access: yesComputer Graphics Forum, EarlyView.
In this paper, we present a high performance procedural model capable of synthesizing and rendering a virtually infinite ocean. Our method exhibits spatial variations as the orientations, speed and choppiness of the waves is parametrized for each frequencies and each point in space. The provided visual abstract exhibits a sunset rendering of a large 40 
Romain Fournier   +4 more
wiley   +1 more source

Wave breaking and transition to turbulence in stratified shear flows

open access: yes, 1996
D. Fritts, J. Garten, Ø. Andreassen
semanticscholar   +1 more source

Primal SPH Solver for Strongly Coupled Multiphase Simulations with High Density Ratios

open access: yesComputer Graphics Forum, EarlyView.
Abstract In recent years, the Smoothed Particle Hydrodynamics (SPH) approach has been increasingly used for multiphase simulations involving interactions between diverse materials. A critical component of an SPH simulator is the pressure solver, which not only facilitates the simulation of compressible or incompressible fluids but also handles contact ...
Jan Bender   +3 more
wiley   +1 more source

Extreme weather and economic crisis in the 1430s in England, and the implications for tenurial change

open access: yesThe Economic History Review, EarlyView.
Abstract The 1430s were characterized by extreme weather conditions, food and fodder shortages, and high mortalities among animals and humans, although the severity of events and their consequences in England have received limited attention. The economic downturn and the depressed customary land market in this decade marked the beginning of the Great ...
Mark Bailey
wiley   +1 more source

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