Results 111 to 120 of about 7,472 (217)
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su +13 more
wiley +1 more source
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao +13 more
wiley +1 more source
Interacting Parallel Fluidic Hysterons
The parallel coupling of fluidic hysterons is introduced, establishing advanced functionalities in inflatable soft systems. A pressure–volume framework reveals how preset volumes Δv∗${\Delta }v^*$ tune nonlinear interactions between hysterons and actuation sequences without changing architecture. Experiments validate the predictions, opening new routes
Katrien Stinissen +2 more
wiley +1 more source
Physics‐Informed Neural Network‐Enabled Forward Prediction and Inverse Design of Ring Origami
This work presents a KRT‐PINN framework that integrates Kirchhoff rod theory with physics‐informed neural networks for the forward prediction and inverse design of ring origami consisting of closed‐loop rods. The framework predicts stable states of segmented rings with prescribed natural‐curvature profiles and determines the natural‐curvature profiles ...
Luyuan Ning +3 more
wiley +1 more source
Dynamic Properties in a Collisional Model for Confined Granular Fluids: A Review. [PDF]
Brito R, Soto R, Garzó V.
europepmc +1 more source
A straightforward method is introduced to produce ion‐gel films with very low surface roughness by employing a solution‐shearing coating process. These ion‐gel films permit the growth of crystalline thin films of various small molecule organic semiconductor molecules directly on top of the ion‐gel layer, thereby enabling “inverted” small molecule ...
Jonathan Perez Andrade +10 more
wiley +1 more source
What triggers seismicity thousands of kilometers away from a mainshock? [PDF]
Huang C, Yang J.
europepmc +1 more source
Ultrasound pretreatment in combination with controlled dehydration at temperatures between 50°C and 60°C is appropriate for producing healthy, acceptable, and shelf‐stable beske (soybean cheese). ABSTRACT Soy cheese, locally known as beske is a protein‐rich product from soymilk but is highly perishable with limited shelf life.
Arise Abimbola Kemisola +3 more
wiley +1 more source
Study on key strata and surface deformation prediction for overburden separation grouting mining in adjacent panel based on foundation beam theory. [PDF]
Shibao L +8 more
europepmc +1 more source

