Results 31 to 40 of about 183,428 (314)
Frontiers in Pharmacology, 2020 Advanced drug carriers for the controlled release of chemotherapeutics in the treatment of malignant tumors have drawn significant notice in recent years. In the current study, microspheres (MPs) loaded with docetaxel (DTX) were prepared using polylactic-
Yuhao Zheng +6 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Factors Influencing the Mechanical Characteristics of a Pile–Soil Interface in Clay Soil
Frontiers in Earth Science, 2020 A series of direct shear tests using a large-scale constant-normal-stiffness direct-shear testing system was conducted to study the factors that influence the mechanical characteristics of a pile–soil interface (PSI) in clay soil. Interfaces of different
Mingyi Zhang +3 more
doaj +1 more source
Shear Rate and Permeability in Water Flooding [PDF]
Transport in Porous Media, 2008 Water breakthrough during oil recovery can be inhibited by the use of novel shear-induced structure additives. These affect the shear rate experienced by fluid inside the rock matrix. We relate this to the permeability for the purpose of applying these novel non-Newtonian materials which thicken viscosity only in the shear range associated with the ...
Reuvers, N.J.W., Golombok, M.
openaire +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
BiosensorsThe currently available point-of-care hemostasis tests are burdened by criticisms concerning the use of different activators and inhibitors and the lack of dynamic flow.
Alessandro Foladore +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Optimizing the flocculation behavior of ultrafine tailings by ultra-flocculation
工程科学学报, 2019 With the continuous pursuit of mineral resources and the development of mineral processing technology, ore is being ground more and more finely, which has resulted in large volumes of ultrafine tailings.
WU Ai-xiang +4 more
doaj +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Effect of Shear Flow on Nanoparticles Migration near Liquid Interfaces
Entropy, 2021 The effect of shear flow on spherical nanoparticles (NPs) migration near a liquid–liquid interface is studied by numerical simulation. We have implemented a compact model through which we use the diffuse interface method for modeling the two fluids and ...
Ali Daher +3 more
doaj +1 more source