Results 41 to 50 of about 11,940,393 (348)
Spiral arm pitch angle and galactic shear rate in N-body simulations of disc galaxies [PDF]
Spiral galaxies are observed to exhibit a range of morphologies, in particular in the shape of spiral arms. A key diagnostic parameter is the pitch angle, which describes how tightly wound the spiral arms are.
R. Grand, D. Kawata, M. Cropper
semanticscholar +1 more source
Fluctuations of energy injection rate in a shear flow [PDF]
We study the instantaneous and local energy injection in a turbulent shear flow driven by volume forces. The energy injection can be both positive and negative. Extremal events are related to coherent streaks. The probability distribution is asymmetric, deviates slightly from a Gaussian shape and depends on the position in shear direction.
Bruno Eckhardt, Joerg Schumacher
openaire +4 more sources
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Analytical theory of forced rotating sheared turbulence: The perpendicular case [PDF]
Rotation and shear flows are ubiquitous features of many astrophysical and geophysical bodies. To understand their origin and effect on turbulent transport in these systems, we consider a forced turbulence and investigate the combined effect of rotation ...
A. A. Townsend+14 more
core +5 more sources
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Extension of Classical Nucleation Theory for Uniformly Sheared Systems
Nucleation is an out-of-equilibrium process, which can be strongly affected by the presence of external fields. In this letter, we report a simple extension of classical nucleation theory to systems submitted to an homogeneous shear flow.
Barrat, Jean-Louis+2 more
core +2 more sources
A study was carried out to determine the effect of higher shear rates (64.5 to 4835 s−1) on the absolute viscosities of different vegetable oils at different temperatures (26 to 90°C).
L. Diamante, Tian Lan
semanticscholar +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source