Results 31 to 40 of about 420,131 (282)

Seismic Response of a Platform-Frame System with Steel Columns [PDF]

open access: yes, 2017
Timber platform-frame shear walls are characterized by high ductility and diffuse energy dissipation but limited in-plane shear resistance. A novel lightweight constructive system composed of steel columns braced with oriented strand board (OSB) panels ...
De Stefani, Lorenzo   +4 more
core   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Analysis of Dowel Action in Reinforced Concrete Beams with Shear Reinforcement

open access: yesCivil and Environmental Engineering, 2021
The shear transfer mechanism was examined to view the contributions of different components of shear transfer such as aggregate interlocking, dowel force and uncracked compression zone.
Joshi Sreenivasa Prasad   +2 more
doaj   +1 more source

Phase transition in a static granular system

open access: yes, 2006
We find that a column of glass beads exhibits a well-defined transition between two phases that differ in their resistance to shear. Pulses of fluidization are used to prepare static states with well-defined particle volume fractions $\phi$ in the range ...
Aste T.   +9 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Forming simulation of a thermoplastic commingled woven textile on a double dome [PDF]

open access: yes, 2008
This paper presents thermoforming experiments and FE simulations of a commingled glass-PP woven composite on a double dome geometry, with the aim of assessing the correspondence of predicted and experimental shear angles.
A. Willems   +7 more
core   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro   +10 more
wiley   +1 more source

Dynamic Precipitation during High‐Pressure Torsion of a Magnesium–Manganese Alloy

open access: yesAdvanced Engineering Materials, EarlyView.
An ultrafine‐grained alloy is produced by high‐pressure torsion of solutionized Mg–1.35 wt% Mn. Precipitation of nanometer‐scale Mn particles during deformation provides pinning sites. This prevents the formation of a bimodal grain structure and results in a finer grain size than for pure Mg.
Julian M. Rosalie, Anton Hohenwarter
wiley   +1 more source

Shear resistance improvement of oil-contaminated ballast layer with rubber shred inclusions [PDF]

open access: yes, 2016
Railway ballast, which form an integral part of rail tracks, is highly susceptible to subsistence due to both vibration transmitted by the passing trains, as well as the breakage of ballasts with repeated impact.
Chan, Chee Ming   +1 more
core  

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